摘要
目的探讨常规磁共振成像(MRI)和氢质子磁共振波谱成像(1H-MRS)在癫痫海马硬化中的诊断价值。方法选取2016年2月至2017年11月在我院治疗的癫痫患者50例,行常规MRI扫描、液体衰减反转恢复序列(FLAIR)、T2W-FLAIR序列、GMonly序列及1H-MRS扫描。结果 MRI检出异常者共29例,检出率为58.00%,准确定位率为68.97%;1H-MRS检出异常者41例,检出率为82.00%,准确定位率为90.24%,1H-MRS检出率和定位准确率明显高于MRI(P<0.05);患侧海马NAA/(Cho+Cr)、NAA/Cr和NAA/Cho分别为(0.44±0.12)、(0.92±0.30)和(1.00±0.53),明显低于对侧海马(P<0.05);患侧和对侧海马Cho/Cr比较差异无统计学意义(P>0.05)。结论 MRI和1H-MRS在癫痫患者海马硬化诊断中有较好的应用价值,其中1H-MRS检出率和定位准确率较高,可定量分析患者脑组织生化代谢异常。
Objective To explore the value of conventional magnetic resonance imaging(MRI)and hydrogen proton magnetic resonance spectroscopyin the diagnosis of hippocampal sclerosis in epileptic patients.Methods A total of 50 cases of epileptic patients who were treated in our hospital from February 2016 to November 2017 were selected,the routine MRI scan,fluid attenuated inversion recovery sequence(FLAIR),T2W-FLAIR sequence,GM-only sequence and 1H-MRS scan were performed.Results A total of 29 cases of abnormal were detected by MRI,the detection rate was 58%and the accurate location rate was 68.97%.41 cases of abnormal were detected by 1H-MRS,the detection rate was 82.00%,the accurate location rate was 90.24%,and the detection rate and location accuracy of 1H-MRS were significantly higher than that of the MRI(P<0.05).The NAA/(Cho+Cr),NAA/Cr and NAA/Cho in the affected side of the hippocampus were(0.44±0.12),(0.92±0.30)and(1.00±0.53),which were significantly lower than those in the contralateral hippocampus(P<0.05).There was no statistically significant difference in Cho/Cr between the affected side and the contralateral hippocampus(P>0.05).Conclusion MRI and 1H-MRS has good application value in the diagnosis of hippocampal sclerosis in epileptic patients,of which 1H-MRS detection rate and location accuracy rate are relatively high,which can quantitatively analyze brain tissue biochemical metabolism abnormalities.
作者
张志强
杨明贵
王东
ZHANG Zhi-qiang;YANG Ming-gui;WANG Dong(Department of Radiology,Nanyang Nanshi Hospital,Nanyang 473065,Henan Province,China)
出处
《中国CT和MRI杂志》
2019年第1期9-11,共3页
Chinese Journal of CT and MRI
关键词
磁共振成像
氢质子磁共振波谱
癫痫
海马硬化
Magnetic Resonance Imaging
Proton Magnetic Resonance Spectroscopy
Epilepsy
Hippocampal Sclerosis
