摘要
目的观察当归芍药散联合壮医药线点灸治疗原发性痛经的效果及其对前列腺素F2α(PGF2α)和前列腺素E2(PGE2)的影响。方法将60例原发性痛经患者随机分为治疗组和对照组各30例,对照组给予布洛芬胶囊口服,治疗组给予当归芍药散同时配合壮医药线点灸,比较两组患者PGE2、PGF2α、痛经程度及疗效。结果治疗组30例患者中治愈、显效、有效、无效分别为15例、5例、8例、2例,总有效率为93.33%;对照组30例患者中治愈、显效、有效、无效分别为8例、5例、6例、11例,总有效率为63.33%,两组总有效率比较差异有统计学意义(P<0.05)。两组患者治疗后症状积分均较治疗前明显降低(P<0.001);两组原发性痛经患者外周血中PGE2含量明显升高,外周血PGF2α的含量明显降低(P<0.001)。结论当归芍药散联合壮医药线点灸治疗原发性痛经可调节血清前列腺素浓度,缓解痛经,提高疗效。
Objective To observe the therapeutic efficacy of Danggui Shaoyao Powder and Zhuang nationality thread moxibustion on primary dysmenorrhea and its effect on prostaglandin F 2α(PGF2α)and prostaglandin E2(PGE2).Methods Sixty patients with primary dysmenorrhea were randomly divided into a therapeutic group and a control group,and each group consised of 30 cases.The control group were treated with oral ibuprofen capsule,and the observation group were treated with Danggui Shaoyao Powder combined with Zhuang nationality thread moxibustion.We compared PGE2,PGF2α,dysmenorrhea degree and therapeutic efficacy between the two groups.Results Among the therapeutic group of 30 patients,15 cases were cured,5 cases were markedly effective,8 cases were effective,and 2 cases were invalid,the total effective rate was 93.33%.Among the control group of 30 patients,8 cases were cured,5 cases were markedly effective,6 cases were effective,and 11 cases were invalid,the total effective rate was 63.33%,comparison of the total effective rate between the two groups showed statistical difference(P<0.05).Compared to pre-treatment scores of symptoms,the post-treatment scores of symptoms in patients of both two groups were significantly decreased(P<0.001).The peripheral blood PGE2 content were significantly increased,and the peripheral blood PGF2a content were significantly decreased in the therapeutic group of patients with primary dysmenorrhea(P<0.001).Conclusion Danggui Shaoyao Powder combined with Zhuang nationality thread moxibustion can regulate the concentration of serum prostaglandin in patients with primary dysmenorrhea,relieve dysmenorrhea and improve the therapeutic efficacy.
作者
林艳明
马卓飞
张红参
Lin Yanming;Ma Zhuofei;Zhang Hongshen(Youjiang Medical University for Nationalities,Baise 533000,Guangxi,China)
出处
《右江民族医学院学报》
2019年第1期83-85,共3页
Journal of Youjiang Medical University for Nationalities
基金
广西科技厅攻关项目(AB16380203)
关键词
当归芍药散
线壮灸
原发性痛经
前列腺素
Danggui Shaoyao Powder
Zhuang nationality thread moxibustion
primary dysmenorrhea
prostaglandins
