摘要
目的探讨高海拔地区生活的老年性黄斑变性(AMD)的危险因素及特点。方法选取105例生活居住在高海拔地区AMD患者作为病例组,同期110例健康人群作为对照组,调查两组研究对象的临床资料。分析高海拔地区AMD的危险因素及特点。结果两组研究对象年龄、高原生活时间、吸烟史、高血压病史、配带遮阳帽或护目镜情况比较差异具有统计学意义(P<0.05)。Logistic回归分析显示:年龄、高原生活时间、吸烟史、高血压是AMD的危险因素,配带遮阳帽或护目镜是AMD的保护因素(OR=8.562、1.605、1.936、1.206、0.284, P<0.05)。结论除年龄、吸烟、高血压等常见原因外,高原生活时间和日光暴露对老年黄斑变性的发病有明显影响。
Objective To discuss the risk factors and characteristics of age-related macular degeneration(AMD) in high altitude areas. Methods A total of 105 AMD patients lived in high altitude were selected as the case group, and 110 healthy people in the same period as the control group. The clinical data of the two groups were investigated. The risk factors and characteristics of AMD in high altitude areas was analyzed. Results Both groups had statistically significant difference in age, plateau life time, smoking history, high blood pressure history, wearing a sunhat or goggles status(P<0.05). Logistic regression analysis showed that age, plateau life time, smoking history, and hypertension were risk factors for AMD, and wearing a sunhat or goggles was a protective factor for AMD(OR=8.562, 1.605, 1.936, 1.206, 0.284, P<0.05). Conclusion In addition to age, smoking, hypertension, high altitude living time and sunlight exposure have a significant impact on the incidence of macular degeneration in the elderly.
作者
刘璟
刘战强
蒋方卫
苏占花
刘玲
LIU Jing;LIU Zhan-qiang;JIANG Fang-wei(Qinghai Oilfield Staff General Hospital (Gansu Dunhuang QinghaiOilfield Staff General Hospital), Qinghai 736202, China)
出处
《中国现代药物应用》
2019年第4期19-20,共2页
Chinese Journal of Modern Drug Application
关键词
高海拔地区
黄斑变性
危险因素
High altitude areas
Macular degeneration
Risk factors
