摘要
调查嘉兴地区体检人员幽门螺杆菌感染情况及其影响因素,为本地区Hp感染防治提供参考。方法测定2860名体检者血清Hp抗体(a Hp),收集其13C-尿素呼气试验和胃镜检查结果,调查其饮酒、抽烟、熬夜、工作性质等情况,并以Logistic回归分析Hp感染的危险因素。结果 a Hp阳性率为27. 27%,其中呼气试验阳性比为35. 0%。呼气试验阳性组胃和十二指肠溃疡发生率高于阴性组而胃炎发生率低于阴性组(χ~2=14. 51,7. 22,21. 35;均P<0. 01)。男性、非体力劳动、年龄小者的饮酒、抽烟或熬夜比例分别高于女性、体力劳动、年龄较大者(χ~2=16. 11,6. 85,7. 01;均P<0. 05)。饮酒、吸烟、熬夜、男性、非体力劳动、低龄是Hp感染的危险因素(OR=1. 651～8. 230,均P<0. 05)。结论嘉兴地区Hp感染率较高,饮酒、吸烟、熬夜、从事非体力劳动、年龄较小的男性是Hp感染的危险人群。
Objective To understand the factors that contribute to Helicobacter pylori (Hp) infection in Jiaxing district with a view to developing scientifically sound measures for the control of Hp infection. Methods Firstly, the serum anti-Hp antibody (aHp) measurements of 2860 physical health examinees were performed. The Results from 13 C-Urea Breathing Test ( 13 C-UBT)and gastroscopy were recorded. Secondly, the behaviors of the subjects in terms of wine drinking, smoking, staying-up-late, and occupation were documented. Lastly, logistic regression analysis was used to examine the risk factors of Hp infection. Results The positive rate of aHp was 27.27% where the positive ratio of 13 C-UBT was 35.0%. The rate of incidence of gastric and duodenal ulcer in the 13 C-UBT-positive group was higher than that of the 13 C-UBT-negative group(χ 2 =14.51, 7.22;P <0.01). The rate of incidence of gastritis was lower than that of the 13 C-UBT-negative group(χ 2 =21.35, P <0.01). Rates of wine drinking, smoking and staying-up-late of males, non-physical workers and the younger were higher than those of females, manual workers and the elder (χ 2 =16.11, 6.85, 7.01;P <0.05). Drinking, smoking, staying up late, male, non-manually jobs and young age are the risk factors for Hp infection ( OR =1.651~8.230, P <0.05). Conclusions There is high rate of incidence of Hp infection in Jiaxing district. Drinking, smoking, staying up late, non physical workers and young males are the risk groups of Hp infection.
作者
吴学虹
王丽燕
李胜兵
WU Xue-hong;WANG Li-yan;LI Sheng-bing(Clinical Laboratory, The First People’s Hospital of Jiashan, Jiashan 314100;Clinical Laboratory, The Second Hospital of Jiaxing, Jiaxing 314000, China)
出处
《健康研究》
CAS
2019年第1期21-24,共4页
Health Research
关键词
体检人员
幽门螺旋杆菌
感染
影响因素
physical examination personnel
Helicobacter pylori
infection
influence factors
