摘要
目的:探讨五拗汤加味联合头孢噻肟治疗老年慢性支气管炎急性加重期的临床疗效。方法:选取2016-2018年笔者所在医院收治的82例老年慢性支气管炎急性加重期患者,随机分为研究组(41例)、对照组(41例)。对照组在头孢噻肟钠基础上口服强力枇杷露进行治疗,研究组在此基础上联合五拗汤进行治疗,治疗1周后观察两组临床疗效及治疗前、后肺功能变化。结果:研究组临床总有效率为97.56%,相较于对照组的87.80%明显更高,差异有统计学意义(P<0.05);治疗前两组FEV1、FVC、PEF等肺功能指标差异无统计学意义(P>0.05),治疗后研究组FEV1、FVC、PEF等指标均显著高于对照组,差异均有统计学意义(P<0.05)。结论:对老年慢性支气管炎患者而言,五拗汤联合头孢噻肟钠是一种理想的治疗方式,可进一步增强临床疗效,改善患者肺功能,促进临床症状及体征的消失,在临床上具有切实可行性及安全性。
Objective:To study the clinical efficacy of modified Wu’Ao Decoction combined with Cefotaxime Sodium in acute exacerbation of chronic bronchitis.Method:A total of 82 elderly patients with acute exacerbation of chronic bronchitis treated from 2016 to 2018 in our hospital were selected.Patients were randomly assigned to two groups,41 cases each group.The control group took Cefotaxime Sodium and Qiangli Pipa syrup,the study group took Wut’Ao Decoction with Cefotaxime Sodium.After 1w of treatment,the clinical efficacy and pulmonary function were probed.Result:The total effective rate in the study group(97.56%)was significantly higher than 87.80%of control group(P<0.05).Before treatment,there were no significant differences in the pulmonary function indicators of FEV1(Forced Expiratory Volume in the first second),FVC(forced vital capacity)and PEF(peak expiratory flow)between two groups(P>0.05),after treatment,the values of FEV1,FVC and PEF in the study group were significantly higher than control group(P<0.05).Conclusion:The Wu’Ao Decoction combined with Cefotaxime Sodium can better increase the clinical efficacy,improve the pulmonary function and relieve the clinical symptoms and signs.It is practicable,feasible and safe in clinical practice.
作者
钟小燕
杨万全
叶瑞航
ZHONG Xiaoyan;YANG Wanquan;YE Ruihang(Longchuan County Hospital of TCM,Longchuan 517300,China)
出处
《中外医学研究》
2019年第3期22-24,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH