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耳穴压丸联合生脉胶囊改善维持性血液透析患者生活质量的临床研究 被引量:4

Clinical Study on Auricular Acupoint Sticking Combined with Shengmai Capsules for Improving Quality of Life in Patients with Maintenance Hemodialysis
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摘要 目的观察耳穴压丸联合生脉胶囊改善维持性血液透析患者生活质量的临床疗效。方法选取2014年3月—2015年12月北京市东直门医院维持性血液透析(MHD)患者46例、第一中西医结合医院MHD患者26例,合计72例,通过随机分组方式将患者分为1、2组,进行前后交叉对照试验。试验分2个阶段进行,第一阶段1组为治疗组、2组为对照组;第二阶段2组为治疗组、1组为对照组。每一阶段均包括8周的治疗期和8周的随访期,完成第一阶段的治疗后,2组均经过4周的洗脱期,再交叉进行第二阶段为期8周的治疗,整个研究过程持续时间为20周。治疗组在常规血液透析的基础上,辅助耳穴压丸联合口服生脉胶囊治疗,对照组仅采用常规血液透析治疗。研究以SF-36评分量表评定患者的生活质量,观察耳穴压丸联合生脉胶囊是否改善血液透析患者生活质量,以及在生理机能(PF)、精力(VT)、健康变化(HT)三个方面的具体体现。结果 72例患者经过2个疗程的治疗后,治疗组患者的生理机能(PF)、精力(VT)、健康变化(HT)评分显著高于对照组(P<0.05),而2组的精神健康(MH)、社会功能(SF)、一般健康状况(GH)、躯体疼痛(BP)、生理职能(RP)、情感职能(RE)评分差异无统计学意义(P>0.05)。结论耳穴压丸联合生脉胶囊能在一定程度上改善维持性血液透析患者生活质量,体现在三方面:生理机能、精力、健康变化。 Objective To observe the clinical effect of auricular acupoint sticking and Shengmai capsules for improving quality of life in patients with maintenance Hemodialysis.Methods 72 patients with maintenance hemodialysis(MHD)were randomly divided into two groups(group one and group two)on average.All of these subjects were selected from Dongzhimen hospital from March 2014 to December 2015.Cross comparison before and after the study was applied.There were two stages in this research.In the first phase,group one was treatment group and group two was the control group.In the second phase,group two was the treatment group,while group one was the control group.Each stage consisted of 8 weeks of treatment period and 8 weeks of following-up.Both groups had a 4-week of washout period after first stage.Then each group switched interventions during the second stage for 8 weeks.The whole research process lasted for 20 weeks.Treatment group received regular hemodialysis,auxiliary earpills combined Shengmai capsules treatment,the control group only received hemodialysis treatment.The Short Form 36 Health Questionnaire(SF-36)was used to assess quality of life of patients to estimate whether uricular acupoint sticking and Shengmai capsules improved quality of life in patients receiving hemodialysis.The improvement embodied concretely in three dimensions(physiological function(PF),energy change(VT),health(HT)).Results After 2 phases of treatment,PF,VT and HT scores of treatment group patients were significantly higher than that of control group(P<0.05).While mental health(MH),social function(SF),general health(GH),body pain(BP),physiological functions(RP)and the functions of emotion(RE)score of both groups had no significant difference(P>0.05).Conclusion Auricular acupoint sticking and Shengmai capsules to a certain extent improve quality of life in patients with maintenance hemodialysis in three aspects:PF,VT and HT.
作者 王平 曹钋 钟剑 李春辉 张蕊 WANG Ping;CAO Po;ZHONG Jian;LI Chunhui;ZHANG Rui(The First Clinical Medical College,Beijing University of Chinese Medicine,Beijing 100029,China;Dialysis Room,Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine,Beijing 100700,China;Dialysis Room,Beijing Hospital of Integrated Traditional Chinese Medicine and Western Medicine,Beijing 100029,China)
出处 《中国中医药现代远程教育》 2019年第5期66-70,共5页 Chinese Medicine Modern Distance Education of China
基金 北京中医药大学校级自主选题项目【No.2013-ZYLC-003】
关键词 耳穴压丸 生脉胶囊 血液透析 生活质量 中成药疗法 auricular acupoint sticking Shengmai capsules Hemodialysis quality of life therapy of Chinese patent drug
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