摘要
目的探究土家族及汉族肿瘤患者药品不良反应的特征。方法对240例土家族及汉族肿瘤患者抗肿瘤药物及相关辅助药物的不良反应进行回顾性分析。结果土家族及汉族肿瘤患者发生ADR的年龄、性别分布及严重程度等均无显著差异(P>0.05),两者引起ADR例数最多的均是抗肿瘤及其辅助药物,ADR类型最多的均是皮肤及附件损害、胃肠系统损害,但两者罹患的肿瘤谱比较,差异有统计学意义(P<0.05)。结论发生ADR的土家族及汉族患者罹患的肿瘤类别存在差异,临床应给予关注。
Objective To explore the characteristics of adverse drug reactions (ADR) in Tujia and Han cancer patients in this region. Methods The adverse reactions of antitumor drugs and related adjunctive drugs in 240 cases of Tujia and Han cancer patients were retrospectively analyzed. Results There were no differences in age, sex distribution and severity of ADR among Tujia and Han cancer patients (P>0.05). Antitumor drugs and related adjunctive drugs caused the most cases of ADR in both Tujia and Han group of patients. The most common types of ADR included skin and appendage lesions, gastrointestinal system damage. There were differences in ADR between the patients with different categories of primary tumors (P<0.05). Conclusion There were differences in tumor types of Tujia and Han patients with ADR and doctors should pay attention to it.
作者
王银辉
张芳
吴玉娇
杨艳玲
WANG Yinhui;ZHANG Fang;WU Yujiao;YANG Yanling(Department of Clinical Medicine,the Central Hospital of Enshi Tujia and Miao Autonomous Prefecture)
出处
《肿瘤药学》
CAS
2018年第6期979-982,共4页
Anti-Tumor Pharmacy
关键词
肿瘤患者
土家族
药品不良反应
Tumor patients
Tujia Population
Adverse drug reactions
