摘要
宫颈癌、子宫内膜癌和卵巢癌是三类高发病率的妇科肿瘤,严重威胁着人类健康。由于肿瘤代谢异常,以及肿瘤本身或其所产生的腹水对消化道的压迫引起进食减少,从而导致患者出现营养问题,围术期妇科肿瘤患者的营养状况影响其临床结局,20%的妇科肿瘤患者死亡原因与营养不良直接相关。本文通过在Pubmed、Embase以及CNKI等数据库检索围术期妇科肿瘤患者营养相关研究文献,对目前所应用的营养筛查、评估、干预方法及进展情况进行了梳理。常用的营养筛查工具包括:营养风险筛查2002、微型营养评估、营养不良通用筛查工具、营养不良筛查工具和营养风险指数。常用的营养评估量表工具包括主观整体评估和患者主观整体评估。此外,使用免疫增强型肠内营养或术后早期口服喂养等营养干预方法有助于缩短围术期妇科肿瘤患者住院时间、降低术后并发症、加速肠道功能恢复、提升免疫功能和营养状况。然而,针对营养干预对生活质量以及长期生存的影响仍有待进一步研究。
Cervical cancer,endometrial cancer and ovarian cancer are three types of gynecological cancer with high incidence,which seriously threaten human health.Nutritional problems happened normally in gynecological cancer patients because of intake less,which induced by tumor metabolic abnormalities and digestive tract oppression.Furthermore,nutritional status of the perioperative patients with gynecological cancer affect the clinical outcome,it has been reported that malnutrition may be responsible for 20%of gynecological cancer deaths.In this article,we reviewed the current methods and progress of nutrition screening,assessment,and intervention in perioperative patients with gynecological cancer through by searching in Pubmed,Embase and CNKI database.Common nutrition screening tools include nutritional risk screening 2002(NRS 2002),mini nutritional assessment(MNA),malnutrition universal screening tool(MUST),malnutrition screening tool(MST)and nutritional risk index(NRI).Common nutrition assessment tools include subjective global assessment(SGA)and patient-generated subjective global assessment(PG-SGA).Previous studies suggested that nutrition intervention by immune-enhanced enteral nutrition or oral supplement helps to shorten the hospital stay,reduce the postoperative complications,accelerate intestinal function recovery,improve immune function and nutritional status for perioperative patients with gynecological cancer.However,the effect of nutrition intervention on quality of life and long-term survival still need to be further studied.
作者
李晖
宁艳辉
许常娟
商维虎
杨芳
LI Hui;NING Yan-hui;XU Chang-juan;SHANG Wei-hu;YANG Fan(Department of Gynaecology and Obstetrics,the 157 Branch of General Hospital of Guangzhou Military Region,Guangzhou510510,China;Beijing Kancare Nutrition Technology Co.,Ltd,Beijing 102206,China;Department of Gynaecology andObstetrics,Nanfang Hospital Southern Medical University,Guangzhou 510515,China)
出处
《肿瘤代谢与营养电子杂志》
2018年第4期337-341,共5页
Electronic Journal of Metabolism and Nutrition of Cancer
基金
国家科技支撑计划(2015BAI13B04)
关键词
营养干预
妇科肿瘤
围术期
Nutrition intervention
Gynecological cancer
Perioperative
