摘要
目的探讨血清骨钙素水平联合CT诊断早期股骨头缺血性坏死的临床价值。方法选取我院收治的92例疑似股骨头早期缺血性坏死患者为研究对象,患者均接受CT检查,并抽取外周血检测血清骨钙素水平,并对CT、血清骨钙素水平检测及二者联合检测对早期股骨头缺血性坏死的诊断价值。结果金标准为MRI,其中金标准证实84例为股骨头早期缺血性坏死,8例为非股骨头早期缺血性坏死。血清骨钙素水平诊断阳性为63例,阴性29例。CT诊断为阳性71例,阴性21例。血清骨钙素水平及CT联合检测诊断阳性77例,阴性15例。血清骨钙素水平及CT联合检测的灵敏性、特异度、符合率、Kappa值均高于骨钙素、CT单独检测(P<0.05)。结论血清骨钙素水平与CT联合诊断股骨头早期缺血性坏死的灵敏度及特异度均较高,具有较高的可行性,临床诊断价值较高。
Objective To explore the clinical value of serum osteocalcin levels combined with CT in the diagnosis of early avascular necrosis of femoral head. Methods Ninety-two patients suspected with early avascular necrosis of femoral head in our hospital were selected as the study objects. All patients underwent CT exumination and peripheral blood was taken to detect levels of serum osteocalcin. To compare the diagnostic value of CT, serum calcitonin levels and their combined detection in early avascular necrosis of femoral head. Results The gold standard was MRI. The gold standard confirmed 84 cases as early avascular necrosis of femoral head and 8 cases as non-femoral head early avascular necrosis.In which, 63 cases were positive, 29 cases were negative diagnosed by the level of serum osteocalcin levels. 71 cases were positive, 21 cases were negative diagnosed by CT. 77 cases were positive, 15 cases were negative diagnosed by serum osteocalcin levels combined with CT. The sensitivity, specificity, coincidence rates and Kappa value of level of serum osteocalcin combined with CT were higher than those of level of serum osteocalcin and CT alone(P<0.05). Conclusion The combined diagnosis of serum osteocalcin level and CT in the diagnosis of early avascular necrosis of femoral head has higher sensitivity and specificity, which has higher feasibility and higher clinical diagnostic value.
作者
薛燕妮
郭灵霞
XUE Yan-ni;GUO Ling-xia(the Hospital of Tongguan County,Weinan 714300;Baoji Maternal and Child Health Care Hospital, Baoji 721000, China)
出处
《临床医学研究与实践》
2019年第7期137-138,共2页
Clinical Research and Practice
