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早期应用瑞舒伐他汀钙治疗急性心肌梗死的效果观察

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摘要 目的:研究早期应用瑞舒伐他汀钙治疗急性心肌梗死的效果。方法:选取于2016年10月至2017年10月期间,在重庆市渝北区人民医院接受治疗的急性心肌梗死患者84例,采用奇偶分组法将患者分为两组,对照组患者接受常规治疗,观察组患者在对照组的基础上接受瑞舒伐他汀钙治疗,比较两组患者的临床疗效。结果:观察组患者临床治疗总有效率为97.62%,高于对照组的73.81%,差异具有统计学意义(P <0.05);观察组患者心血管事件再次发生率为9.52%(4/42),低于对照组的26.19%,差异具有统计学意义(P <0.05);两组患者的肌酸激酶同工酶、心肌肌钙蛋白的指标均得到降低,观察组患者的降低幅度多于对照组;观察组超敏C反应蛋白升高幅度低于对照组,差异具有统计学意义(P <0.05)。结论:急性心肌梗死患者早期应用瑞舒伐他汀钙治疗,能够减少对患者心肌的损伤,降低患者再次心血管事件再次发生率,提高治疗效果。
作者 贾智
出处 《深圳中西医结合杂志》 2019年第1期141-142,共2页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
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  • 1Di Sciascio G, Patti G, Paseeri V, et al. Efficacy of atorvastatin reload in patients on chronic statin therapy undergoing percutaneous coro- nary intervention : results of the ARMYDA-RECAPTURE( Atorvasta- lin [br Reduction of Myocardial Damage During Angioplasty) Ran- domized Trial[ Jl. J Am Coil Cardiol,2009,54(6) :558 -565.
  • 2Masuda J,Tanigawa T, Yamada T, et al. Effect of Combination thera- py of ezetimibe and rosuvastatin on regression of coronary atheroscle- rosis in patients with coronary artery disease~ J]. Int Heart J ,2015, 56 ( 3 ) :278 - 285.
  • 3Kostapanos MS, Rizos CV, Elisaf MS. Benefit-risk assessment of ro- suvastatin in the treatment of atherosclerosis and related diseases [J]. Drag Saf,2014,37(7) :481 -500.
  • 4Garg N, Krishan P, Syngle A. Rosuvastatin improves endothelial dys- tunetion in ankylosing spondylitis [ J ]. Clin Rheumatol, 2015,34(6) :1065 - 107l.
  • 5Funderburg NT, Jiang Y, Debanne SM, et al. Rosuvastatin reduces vascular inflammation and T-cell and monocyte activation in HIV-in- fected subjects on antiretroviral therapy[ J ]. J Acquir Immune Defic Syndr,2015,68(4) :396 -404.
  • 6~ilhav~ J, Zfdek V, Landa V, ct ah Rosovastatin can block pro-in- flammatory actions of transgenic buman C-~activc protein withoul reducing its circulating levels [ J ]. Cardiovasc Ther,2014,32 ( 2 ) :59 -65.
  • 7Kim MC, Ahn Y, Cho KH, et al. Early statin therapy within 48 hours decreased one-year major adverse cardiac m,ents in patienl with a- cute myocaMial infarction~ J]. Int Heart J ,2011,52( 1 ) : 1 - 6.
  • 8An'ivi A, Tanzilli G, Puddu PE, et al. Rosuvastatin was Effective i~, Acute Heart Failure and Slow Co~vnary Flow:A Hypothesis-genera- ting Case Report [ J ]. Open Cardiovasc Med J,2013,7 : 12 - 15.
  • 9Garg N, Krishan P,Syngle A. Rosuvastatin improves endothelial dys- function in ankylosing spondylitis [ J ]. Clin Rheumatol, 2015,34 (6) :1065 - 1071.
  • 10Mahalwar R,Khanna D. Pleiotropic antioxidant potential of rosuvas- tatin in preventing cardiovascular disorders [ J ]. Eur J Pharmacol, 2013,711 ( 1/3 ) :57 - 62.

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