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血清IgG4及联合CA19-9对自身免疫性胰腺炎的诊断价值 被引量:8

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摘要 检测自身免疫性胰腺炎(AIP)、胰腺癌、急性胰腺炎、慢性胰腺炎患者血清IgG4、CA19-9水平,AIP患者的血清IgG4水平显著高于其他胰腺相关疾病(P =0.000)。对AIP及胰腺癌患者进行鉴别诊断,以IgG4 >1.95 g/L为界值诊断AIP的敏感度、特异度分别为78. 6%、96.4%;以CA19-9 < 155. 72 U/ml为界值诊断AIP的敏感度、特异度分别为92. 9%,60. 7%;以两者联合诊断AIP的敏感度、特异度为71.4%,96.4%;当IgG4 > 1.95 g/L 或 CA19-9 < 155.72 U/ml 时诊断 AIP 的敏感度、特异度为 100%、60. 7%。联合检测血清IgG4、CA19-9水平有助于提高对AIP与胰腺癌的鉴别诊断能力。
出处 《中华胰腺病杂志》 CAS 2019年第1期59-62,共4页 Chinese Journal of Pancreatology
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