摘要
结核性脑膜炎(tuberculous meningitis,TBM)是肺外结核中最严重的临床表现类型,具有较高的病死率及致残率,故早期、快速诊断及鉴别诊断TBM对疾病的治疗和预后至关重要。笔者通过综述近年来脑脊液(cerebrospinal fluid,CSF)检测在TBM早期诊断及与化脓性脑膜炎、病毒性脑膜炎(viral meningitis,VM)和新型隐球菌性脑膜炎(cryptococcul neoformans meningitis,CNM)的鉴别诊断方法,旨在为TBM的早期诊断与鉴别诊断提供一定的诊疗思路。
Tuberculous meningitis (TBM) is the most serious type of extra-pulmonary tuberculosis, which usually causes higher mortality and disability rate. So early and rapid diagnosis of TBM, as well as differential diagnosis with other diseases are crucial for TBM treatment and its prognosis. In this paper, we did a systemically review on the research progress of cerebrospinal fluid testing application in early diagnosis of TBM and in differential diagnosis with pyogenic meningitis, viral meningitis (VM) and cryptococcul neoformans meningitis (CNM) in recent years, aiming to provide some ideas or references for the early diagnosis and differential diagnosis of TBM.
作者
王赛赛
马艳
刘洋
WANG Sai-sai;MA Yan;LIU Yang(Department of Epidemiology, Beijing Chest Hospital, Capital Medical University, Beijing Tuberculosis and Thoracic Tumor Institute, Beijing 101149, China)
出处
《中国防痨杂志》
CAS
CSCD
2019年第1期95-101,共7页
Chinese Journal of Antituberculosis
基金
“十三五”国家科技重大专项(2017ZX10201301-004)
北京市医院管理局“登峰”人才培养计划(DFL20181601).
关键词
结核
脑膜
脑脊髓液
早期诊断
诊断
鉴别
实验室技术和方法
综述
Tuberculosis, meningeal
Cerebrospinal fluid
Early diagnosis
Diagnosis, differential
Laboratory techniques and methods
Review
