摘要
目的:研究大柴胡汤对照西药治疗急性胆囊炎的疗效优势。方法:检索CNKI、VIP、Wan Fang、CBM四个数据库,搜索大柴胡汤治疗急性胆囊炎的临床随机对照试验。经提取资料并偏倚风险评估。采用Rev Man 5. 3进行异质性检验、效应量合并、发表偏倚分析。结果:共纳入26个试验,共计2368例患者。Meta分析结果显示:"大柴胡汤加减vs西药"有显著疗效优势(P <0. 0001);大柴胡汤加减联合西药相较于西药治疗急性胆囊炎显著疗效优势(P <0. 00001);亚组分析显示各个亚组大柴胡汤联合西药组均有显著疗效优势。结论:大柴胡汤治疗急性胆囊炎在临床总有效率方面有显著优势。但上述结论尚需更多高质量数据加以验证。
Objective: To evaluate the efficacy of Macro-Bupleuri Decoction in treating acute cholecystitis. Methods: We searched the randomized controlled trials of Macro-Bupleuri Decoction in the treatment of acute cholecystitis from CBM,CNKI,VIP and Wan Fang Database. The obtained data was extracted,evaluated and analyzed by two estimators by using the Cochrane Collaboration’s Rev Man 5. 3. Results: A total of 26 trials involving 2368 patients were included. The results of Meta-analyses showed that there was a significant therapeutic advantage of Macro-Bupleuri Decoction in treating acute cholecystitis( P <0. 0001). Macro-Bupleuri Decoction combined with western medicine showed a superiority than Western medicine obviously( P < 0. 00001). The subgroup analysis showed that each subgroup of Macro-Bupleuri Decoction combined with Western medicine group had significant therapeutic advantage. Conclusion: Macro-Bupleuri Decoction in treating acute cholecystitis has a significant advantage. Further large scale randomized comparison trials are needed to validate to test and verify the conclusion above.
作者
陆艾阳子
刘玉焕
高卉
佟鑫
宋俊生
LU Aiyangzi;LIU Yuhuan;GAO Hui;TONG Xin;SONG Junsheng(Tianjin University of TCM ,Tianjin 300193 ,China;Hebei Provinical Hospital of TCM ,Shijiazhuang 051000, Hebei,China)
出处
《辽宁中医杂志》
CAS
2019年第3期453-459,共7页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金项目(81373891)
关键词
急性胆囊炎
大柴胡汤
临床总有效率
系统评价
META分析
acute cholecystitis
Macro - Bupleuri Decoction
total effective rate
systematic review
Meta - analysis
