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磁控胶囊胃镜在上消化道疾病筛查中的应用 被引量:11

Application of magnetically controlled capsule endoscopy in upper gastrointestinal tract disease screening
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摘要 目的探讨磁控胶囊胃镜(MCE)在上消化道疾病筛查中的可行性、安全性,并分析影响检查效率的因素。方法选取2017年3月—2018年3月于蚌埠医学院第一附属医院消化科行MCE检查的有上消化道症状的患者60例,记录患者胃内主要解剖部位观察情况、胃黏膜可视度、胶囊食管通过时间、上消化道疾病检出情况、检查完成及不适反应发生情况,其中30例于前后4周均行胃镜检查,记录胃镜下疾病检出情况,评估MCE操作的安全性、可行性、耐受性、疾病检出率及年龄对食管通过时间的影响。结果 60例患者中贲门、胃底、胃体、胃角、胃窦、幽门检查完成率分别为85.00%、88.33%、100.00%、95.00%、98.33%和100.00%。60例患者中,96.70%的患者胃黏膜可视情况良好。年龄≥60岁与年龄<60岁患者食管通过时间比较差异无统计学意义。其中43例发现上消化道病变,阳性诊断率为71.67%(43/60),30例患者检查前后4周内行胃镜检查,两者检查结果一致率为90.0%(27/30)。60例患者均顺利完成MCE检查,出现不适反应1例,胶囊均在1周内顺利排出。结论相较于胃镜检查,MCE对上消化道病变有较高检出率,并且检查过程无创、可控,可用于上消化道疾病的筛查。 Objective To explore the feasibility, safety and some factors influencing the efficiency of magnetically controlled capsule endoscopy(MCE) in upper gastrointestinal tract disease screening. Methods Sixty patients with upper gastrointestinal symptoms undergoing MCE in our hospital between March 2017 and March 2018 were selected to record the main anatomical site within the stomach esophagus, gastric mucosa visibility, and time for capsule through gastrointestinal tract, detection of upper gastrointestinal disease, success rate of inspection and incidence of discomfort. Thirty of 60 cases underwent gastroscopy at 4 weeks before and after MCE to detect diseases. The operation safety, feasibility and tolerance of MCE, disease detection rate and the influence of age on esophagus through time were evaluated. Results In 60 patients, the completion rates of cardiac examination, gastric fundus examination, gastric body examination, gastric Angle examination, gastric sinus examination and pylorus examination were 85.00%, 88.33%, 100.00%, 95.00%, 98.33% and 100.00%, respectively. There was no statistically significant difference in the time of capsule through esophageal tract between the patients aged 60 y and less than 60 y. Among them, 43 cases of upper digestive tract lesions were found, with a positive diagnosis rate of 71.67%(43/60), and 30 patients underwent gastroscopy within 4 weeks before and after the examination, with a consistent rate of 90.0%(27/30). All 60 patients successfully finished MCE examination, and 1 patient suffered discomfort, and the capsule was discharged within 1 week. Conclusion Compared with gastroscopy, MCE has a high detection rate of upper digestive tract lesions, and the examination process is noninvasive and controllable, which can be used for the screening of upper digestive tract diseases.
作者 陈雨霏 王启之 柯希权 朱玉 刘晓阳 邓晓晶 CHEN Yu-fei;WANG Qi-zhi;KE Xi-quan(Department of Gastroenterology,the First Affiliated Hospital of Bengbu Medical College,Bengbu,Anhui 233004,China)
出处 《中华全科医学》 2019年第4期543-546,600,共5页 Chinese Journal of General Practice
基金 安徽省教育厅2018年度高校优秀拔尖人才培育资助项目(gxgwfx2018052)
关键词 磁控胶囊胃镜 上消化道疾病 胃镜 非侵入性检查 Magnetically controlled capsule endoscopy Upper gastrointestinal tract disease Gastroscope Non-invasive testing
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