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SPECT/CT融合显像在继发性甲状旁腺功能亢进症中的临床价值 被引量:6

The diagnostic value of ^(99m) Tc-sestamibi SPECT/CT in secondary hyperparathyroidism
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摘要 目的:探讨术前^(^(99m) ) Tc-甲氧异腈(MIBI)核素双时相显像与SPECT/CT融合显像在继发性甲状旁腺功能亢进症中的临床价值。方法:回顾分析经病理证实的38例继发性甲状旁腺功能亢进症患者术前^(99m) Tc-MIBI核素双时相显像与SPECT/CT融合显像的影像资料。结果:^(99m) Tc-MIBI核素双时相显像与SPECT/CT融合显像诊断继发性甲状旁腺功能亢进症的灵敏度分别为86.52%、95.74%;统计分析显示两者之间差异有统计学意义。结论:术前^(99m) Tc-MIBI核素SPECT/CT融合显像对继发性甲状旁腺功能亢进症的评估优于核素双时相显像,SPECT/CT融合显像是继发性甲状旁腺功能亢进症术前定位理想的检查方法。 Objective: To explore the clinical value of dual-phase 99m Tc-sestamibi(MIBI) scintigraphy and SPECT/CT imaging in diagnosing secondary hyperparathyroidism. Methods: Retrospectively analyzed the image features of dual-phase 99m Tc-MIBI scintigraphy and SPECT/CT of 38 patients with secondary hyperparathyroidism, which were confirmed by postoperative pathology. Results: The sensitivity of 99m Tc-MIBI scintigraphy and SPECT/CT in diagnosing secondary hyperthyroidism was86.52% and 95.74% respectively. There were significant difference between dual-phase 99m Tc-MIBI scintigraphy and SPECT/CT.Conclusions: Preoperative99m Tc-MIBI SPECT/CT imaging is significantly better than dual-phase 99m Tc-MIBI scintigraphy in evaluating secondary hyperparathyroidism.99m Tc-MIBI SPECT/CT imaging is an ideal examination method for secondary hyperparathyroidism in preoperative location.
作者 陈正国 刘启榆 吴春燕 陈娇 何川东 CHEN Zheng-guo;LIU Qi-yu;WU Chun-yan;CHEN Jiao;HE Chuan-dong(Department of Radiology, Central Hospital of Mianyang, Mianyang Sichuan 621000,China)
出处 《中国临床医学影像杂志》 CAS 2019年第3期169-173,共5页 Journal of China Clinic Medical Imaging
关键词 甲状旁腺功能亢进症 继发性 99M锝甲氧基异丁基异腈 体层摄影术 发射型计算机 单光子 Hyperparathyroidism, secondary Technetium tc 99m sestamibi Tomography, emission-computed, single-photon
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  • 1Taubman ML, Goldfarb M, Lew JI. Role of SPECT and SPECT/ CT in the Surgical Treatment of Primary Hyperparathyroidism[J]. Int J Mol Imaging, 2011, 2011: 141593.
  • 2Femandez-Ranvier GG, Khanafshar E, Jensen K, et al. Parathy- roid carcinoma, atypical parathyroid adenoma, or parathyromatosis? [J]. Cancer, 2007, 110(2): 255-264.
  • 3Coakley A J, Kettle AG, Well CP, et al. 99Tc sestamibi-a new agent for parathyroid imaging [J]. Nucl Mde Commun, 1989, 10 (11): 791-794.
  • 4Hetrakul N, Civelek AC, Stagg CA, et al. In vitro accumulation of technetium-99m-sestamibi in human parathyroid mitochondria [J]. Surgery, 2001, 130(6): 1011-1018.
  • 5Moralidis E. Radionuclide parathyroid imaging: a concise, updated review[J]. Hell J Nucl Med. 2013. 16(2): 125-133.
  • 6Burke JF, Naraharisetty K, Schneider DF, et al. Early-phase technetium-99m sestamibi scintigraphy can improve preoperative localization in primary hyperparathyroidism [J]. Am J Surg, 2013, 205(3): 269-273.
  • 7Sehachter PP, Issa N, Shimonov lVl, et al. Early, postinjeetion MIBI-SPECT as the only preoperative localizing study for mini- mally invasive parathyroidectomy [J]. Arch Surg, 2004, 139(4): 433-437.
  • 8Noda S, Onoda N, Kashiwagi S, et al. Strategy of operative treat- ment of hyperparathyroidism using US scan and (99m)Tc-MIBI SPECT/CT[J]. Endoc J, 2014, 61(3): 225-230.
  • 9Tokmak H, Demirkol MO, Alagol F, et al. Clinical impact of SPECT-CT in the diagnosis and surgical management of hyper- parathyroidism[J]. Int J Clin Exp Med, 2014, 7(4): 1028-1034.
  • 10Pons F, Torregrosa JV, Fuster D. Biological factors influencing parathyroid localization [J]. Nucl Med Commun, 2003, 24(2): 121-124.

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