摘要
目的:观察清热祛瘀汤治疗围绝经期功能性子宫出血的临床疗效。方法:中药治疗组32例运用中药清热祛瘀汤治疗;西药对照组30例,出血量少者用西药雌孕联合用药,出血量多者用诀诺酮治疗。经过3个月经周期的治疗(每个周期20天),比较两组的临床治疗效果、出血停止时间、复发率以及内分泌情况[卵泡刺激素(Follicle Stimulating Hormone,FSH)、黄体生成素(Luteinizing Hormone,LH)和雌二醇(Estradiol,E2)]。结果:中药治疗组和西药对照组的止血疗效总有效率分别为90.6%和66.7%。中药治疗组疗效优于西药对照组,两组比较差异有显著统计学意义(P <0.05)。中药治疗组第一个月复发率为6.3%,第二个月为9.4%;第三个月为9.4%,西药对照组复发率第一个月为43.3%,第二个月为23.3%,第三个月为10.0%,中药治疗组治疗效果显著优于西药对照组(P <0.05);两组治疗均可升高血清E2水平,降低FSH、LH水平,但中药治疗组效果明显优于西药对照组(P <0.05)。结论:围绝经期功能性子宫出血患者采用中药治疗的临床效果显著,可缩短止血时间,降低复发率,在临床上有较好的应用价值。
Objective:To observe the clinical efficacy of the Qingre Quyu decoction(清热祛瘀汤)on functional uterine bleeding perimenopause.Methods:32 cases in the TCM treatment group were treated with the Qingre Quyu decoction.The western medicine control group of 30 cases was treated with estradiol and progesterone in patients with less bleeding,bleeding cases treated with norethisterone.After three menstrual cycles of treatment(20 days per cycle),the clinical therapeutic effects,bleeding time,recurrence rate and endocrine(FSH,LH and E2)were compared in two groups.Results:The total efficiency on hemostasis in the TCM treatment group and the western medicine control group was 90.6% and 66.7% respectively.The curative effect in the TCM treatment group is better than that in the western medicine control group.There was significant differences between groups(P<0.05).The recurrence rate in the first month in the TCM treatment group was 6.3%,9.4% in the second month,9.4% in the third month.In the western medicine control group,recurrence rate was 43.3% in the first month,23.3% in the second month,10.0% in the third month,and the treatment effect in the TCM treatmenc group was significantly better than that in the western medicine control group(P<0.05).Treatment can increased the level of serum E2,reduced the level of FSH and LH,but the effect in the TCM treatment group was obviously better than the western medicine control group(P<0.05).Conclusion:TCM medicine on perimenopausal dysfunctional uterine bleeding showed clinical effects,which can shorten the time of hemostasis and reduce the recurrence rate,with good clinical value in clinical application.
出处
《中医临床研究》
2019年第8期103-106,共4页
Clinical Journal Of Chinese Medicine
基金
开封市科技发展计划项目<针灸治疗卵巢储备功能减退的临床研究>项目编号:110305
关键词
围绝经期功能性子宫出血
中药治疗
清热祛瘀汤
Perimenopausal functional uterine bleeding
TCM medicine treatment
The Qingre Quyu decoction
