摘要
乳腺癌是目前女性发病率最高的恶性肿瘤。早期发现乳腺病变并进行良恶性鉴别,直接影响临床治疗决策,并关系到乳腺癌患者预后。乳腺肿瘤通常血管富集,对比增强能谱乳腺X线摄影(CESM)技术基于碘剂的K边缘效应,通过静脉注射对比剂后对乳腺组织同时进行高、低能量X线摄片,经处理后获得直接反映碘对比剂在腺体内分布情况的减影图像,消除了腺体重叠干扰,显示病灶血供状态,从而可更敏感地发现隐藏于腺体中的小病灶,准确评估病变形态、范围,并进行定性诊断。本文对CESM在乳腺癌临床诊断中的应用和进展进行综述。
Breast cancer is the most common cancer in female population.Early detection of breast lesions and proper differentiation will directly impact on clinical treatment strategy and is related with prognosis.Breast tumors are usually rich in vascularity.Contrast-enhanced spectral mammography (CESM),based on K-edge effect of iodine,can acquire images of iodine contrast distribution in breasts through special computing and subtraction of images with both low- and high-energy X-ray exposures after intravenous induction of iodinated contrast media.It can eliminate the disturbance caused by overlapping breast tissues and demonstrate blood supply of the lesions,thus is sensitive to small lesion,more accurate in tumor delineating and able to help diagnosing.The current clinical applications and progresses of CESM were reviewed in this article.
作者
曲玉虹
陈倩倩
曹崑
QU Yuhong;CHEN Qianqian;CAO Kun(Department of Radiology,Peking University Cancer Hospital & Institute,Key Laboratory of Carcinogenesis and Translational Research,Beijing 100142,China)
出处
《中国医学影像技术》
CSCD
北大核心
2019年第4期511-514,共4页
Chinese Journal of Medical Imaging Technology
基金
北京市科委医药协同科技创新研究专项(Z181100001918001)
北京市医院管理局重点医学专业发展计划(ZYLX201803)
国家重点研发计划"重大慢性非传染性疾病防控研究"专项(2017YFC1309101
2017YFC1309104)
北京市百千万人才工程项目(2017A13)
关键词
乳腺肿瘤
对比剂
能谱成像
乳房X线摄影
breast neoplasms
contrast media
spectral imaging
mammography
