摘要
慢性丙型肝炎在全球广泛分布,有相当一部分患者将发展为肝硬化或肝癌。目前仍无有效的丙肝疫苗。聚乙二醇干扰素α联合利巴韦林是主要的临床治疗方法。白介素28B基因多态性是其疗效的重要影响因素。本文综述了白介素28B基因多态性与抗丙型肝炎病毒疗效的相关性,以供参考。
A significant number of Chronic hepatitis C patients who distribute globally will develop cirrhosis or liver cancer.There is currently no vaccine for hepatitis C.A combination therapy with pegylated interferon α and ribavirin has been used as a main clinical therapy.Interleukin 28 B single nucleotide polymorphism is a significant factor for antiviral therapy efficiency.This review describes the relationship between single nucleotide polymorphism of Interleukin 28 B and the antiviral therapy efficiency,which will provide reference.
作者
吴汉洲
Wu Han-zhou(Xiamen Biosteed Gene Expression Tech.Co.,Ltd.,Xiamen 361028,China)
出处
《海峡药学》
2019年第3期1-4,共4页
Strait Pharmaceutical Journal
