摘要
目的探究血清维生素D水平对子宫内膜异位症的评估价值。方法选取本院2016年1月至2017年10月收治的198例子宫内膜异位症和卵巢其他肿瘤患者为研究对象,根据病理结果不同将其分为观察组(子宫内膜异位症,102例)和对照组(卵巢其他肿瘤,96例),比较两组患者血清维生素D水平,分析其对子宫内膜异位症的评估价值。结果两组患者Ca^(2+)、25-羟维生素D_2[25-hydroxyvitaminD_2,25-(OH)D_2]水平比较均无显著差异(P_均> 0.05)。观察组患者25-羟维生素D_3[25-hydroxyvitaminD_3,25-(OH)D_3]和维生素D水平均显著低于对照组(P_均<0.05)。观察组中美国生殖医学学会(American Society for Reproductive Medicine,ASRM)分期Ⅰ～Ⅱ期和Ⅲ～Ⅳ期患者Ca^(2+)、25-(OH)D_2水平比较均无显著差异(P_均> 0.05);ASRM分期Ⅰ～Ⅱ期患者25-(OH)D_3和维生素D水平均显著高于Ⅲ～Ⅳ期患者(P_均<0.05)。观察组中痛经患者与无痛经患者Ca^(2+)、25-(OH)D_2、25-(OH)D_3、维生素D水平比较均无显著差异(P_均> 0.05)。结论子宫内膜异位症患者维生素D水平明显低于卵巢其他肿瘤患者,ASRM不同分期的子宫内膜异位症患者维生素D水平亦不同,可根据维生素D水平评估子宫内膜异位症及其病情严重程度。
Objective To explore the value of serum vitamin D level in the evaluation of endometriosis.Method 198 patients with endometriosis and other ovarian tumors in our hospital from January 2016 to October 2017 were selected as the subjects of the study.According to the different pathological results,they were divided into observation group(endometriosis,102 cases)and control group(other ovarian tumors,96 cases),analysis of its evaluation value in endometriosis.Result There were no significant differences in the levels of Ca^2+and 25-hydroxyvitamin D2[25-(OH)D2]between the two groups(Pall>0.05).The levels of 25-hydroxyvitamin D3[25-(OH)D3]and vitamin D in observation group were significantly lower than those in control group(Pall<0.05).There were no significant differences in the levels of Ca^2+and 25-(OH)D2 between stageⅠ~Ⅱand stageⅢ~Ⅳof American Society of Reproductive Medicine(ASRM)in observation group(Pall>0.05).The levels of 25-(OH)D3 and vitamin D in patients with ASRM stageⅠ~Ⅱwere significantly higher than those in patients with stageⅢ~Ⅳ(Pall<0.05).There were no significant differences in Ca^2+,25-(OH)D2,25-(OH)D3 and vitamin D levels between dysmenorrhea patients and non-dysmenorrhea patients in observation group(Pall>0.05).Conclusion The levels of vitamin D in patients with endometriosis were significantly lower than those in patients with other ovarian tumors,and the levels of vitamin D in patients with endometriosis in different stages of ASRM were also different.Endometriosis and its severity can be evaluated according to vitamin D levels.
作者
李秋敏
袁峰
王亚琴
LI Qiu-min;YUAN Feng;WANG Ya-qin(Department of Obstetrics,Shaanxi Provincial People's Hospital,Xi'an 710068,China)
出处
《中国医学前沿杂志（电子版）》
2019年第3期128-131,共4页
Chinese Journal of the Frontiers of Medical Science(Electronic Version)
