摘要
目的:评估3D快速黑血管壁磁共振成像(3D T1-SPACE)技术对基底动脉狭窄病变的诊断价值。方法:回顾性分析54例基底动脉狭窄患者的3D T1-SPACE图像和DSA图像。对3D T1-SPACE图像进行评分,并在3D T1-SPACE和DSA图像中测量病变狭窄程度。评价3D T1-SPACE测量结果与DSA测量结果的相关性和信度;使用Bland-Altman图评价3D T1-SPACE测量结果与DSA测量结果的一致性。以DSA为金标准,计算3D T1-SPACE技术诊断基底动脉重度狭窄的一致率、灵敏度、特异度、阳性预测值、阴性预测值、阳性似然比和阴性似然比。结果:54例患者(41例男性,13例女性)均顺利完成基底动脉3D T1-SPACE扫描。54根基底动脉中,剔除2根评分为1分的血管。图像质量评分为(3.14±0.57)分。3D T1-SPACE测得的基底动脉狭窄率(37.80±16.29)%稍大于DSA上测得的狭窄率(37.06±16.17)%,二者比较,差异无统计学意义(P=0.11);两种成像方式的测量结果相关性强(r=0.979,P<0.001);组内相关系数示3D T1-SPACE与DSA对基底动脉狭窄的诊断信度高(ICC=0.99, 95%CI:0.98,0.99,P<0.001);Bland-Altman图示3D T1-SPACE测量结果与DSA测量结果具有高一致性。以DSA为金标准,3D T1-SPACE技术对基底动脉重度狭窄诊断的一致率、灵敏度、特异度、阳性预测值、阴性预测值、阳性似然比和阴性似然比分别为92.3%,85.7%,96.4%,95.5%,90.0%,24.5和0.13。结论:3D T1-SPACE技术对基底动脉狭窄病变具有较高的诊断价值。
Objective: To evaluate the accuracy and application value of Three-Dimensional Variable-Flip-Angle Turbo Spin-Echo(3 D T1-SPACE) for the diagnosis of basilar atherosclerotic disease. Methods: 54 patients were retrospectively evaluated with 3 D T1-SPACE and DSA images. Basilar artery stenosis obtained from 3 D T1-SPACE and DSA were independently determined. Spearman rank-order correlation coefficient was used to assess the correlation. Bland-Altman plots and intraclass correlation coefficient(ICC) were used to assess the agreement. The consistency rate, sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio were used to assess the diagnostic ability of 3 D T1-SPACE technique. Results: A total of 54 patients(41 men, 13 women) received 3 D T1-SPACE scanning and DSA successfully. There were excellent correlation and agreement between 3 D T1-SPACE and DSA images in measuring luminal stenosis(r=0.979, P<0.001;ICC, 0.99;95% CI: 0.98-0.99,P<0.001). Bland-Altman plots showed that the two modalities were in good consistency in evaluating the degree of stenosis. The consistency rate, sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio of 3 D T1-SPACE in diagnosing severe basilar artery stenosis were 92.3%,85.7%,96.4%,95.5%,90.0%,24.5 and 0.13, respectively. Conclusions: 3 D T1-SPACE is a noninvasive and accurate method in diagnosing basilar artery atherosclerotic disease.
作者
汪振佳
樊昭阳
刘文
于薇
WANG Zhenjia;FAN Zhaoyang;LIU Wen;YU Wei(Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Diseases, Beijing 100029, China)
出处
《心肺血管病杂志》
2019年第3期284-289,共6页
Journal of Cardiovascular and Pulmonary Diseases
