低转运肾性骨病无创性诊断的研究进展被引量：2

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摘要矿物质和骨代谢异常(mineral and bone disorder,MBD)是慢性肾脏病(chronic kidney disease,CKD)患者常见的并发症之一。在如今慢性肾脏病患者全因和心血管死亡率均有增加的情况下,MBD的早期诊断和治疗能够提高慢性肾脏病患者的生活质量和生存率,有深刻的临床意义。肾性骨病是慢性肾脏病伴随的骨代谢异常,其诊断的金标准为骨活检。骨活检操作有创、复杂,临床医生并不将其作为诊断肾性骨病的首选方式。在CKD-MBD发病率逐渐升高的背景下,血清学标志物如血清钙磷、甲状旁腺素、骨型碱性磷酸酶水平结合骨影像学检查成为无创性诊断肾性骨病的常用方法。本文主要对低转运肾性骨病的无创性诊断方法进行综述。

作者郑博文王瑞强

机构地区郑州大学第一附属医院肾内科

出处《河南医学研究》 CAS 2019年第8期1536-1536,F0003,共2页 Henan Medical Research

基金河南省医学科技攻关计划项目(201403046) 河南省科技厅攻关项目(162102310198)

关键词肾性骨病低转运无创性诊断

分类号 R692 [医药卫生—泌尿科学]

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参考文献3

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