摘要
帕金森病(Parkinson’s disease,PD)是黑质多巴胺能神经元变性引起的一种神经退行性疾病,在中老年人群中发病率较高。PD运动症状临床表现中四大主症是运动迟缓、静止性震颤、肌强直和姿势平衡障碍。近年来非运动症状,如神经精神症状、自主神经功能障碍、睡眠障碍、感觉障碍也逐渐被大家认识。其中膀胱功能障碍是自主神经功能障碍中最常见的症状之一,严重影响PD患者的生活质量[1],越来越受到关注。本文对近年有关PD的膀胱功能障碍的研究做一陈述。
Parkinson's disease (PD) is a neurodegenerative disease caused by degeneration of dopaminergic neurons in the substantia nigra.It has a high incidence in the middle aged and elderly population.The four main symptoms in the clinical manifestations of PD motor symptoms are bradykinesia,resting tremor ,myotonia and posture balance disorder.In recent years,non motor symptoms such as neuropsychiatric symptoms,autonomic dysfunction, sleep disorders,and sensory disturbances have gradually become recognized.Among them,bladder dysfunction is one of the most common symptoms of autonomic dysfunction,which seriously affects the quality of life of PD patients,and is receiving more and more attention.This article makes a statement on the research of bladder dysfunction in PD in recent years.
作者
周玉霞
卢宏
ZHOU Yuxia;LU Hong(The First Affiliated Hospital of Zhengzhou University,Zhengzhou450052,China)
出处
《中国实用神经疾病杂志》
2019年第3期337-342,共6页
Chinese Journal of Practical Nervous Diseases
关键词
帕金森病
神经退行性疾病
多巴胺能神经元变性
膀胱功能障碍
自主神经功能障碍
下尿路症状
Parkinson's disease
Neurodegenerative diseases
Dopaminergic neuron degeneration
Bladder dysfunction
Autonomicdysfunction
Lower urinary tract symptoms
