摘要
目的研究不同的经皮冠状动脉介入治疗(PCI)时间对冠状动脉综合征(ACS)患者预后的影响。方法选取汉中市略阳县人民医院心血管内科2013年6月至2017年6月收治且行PCI治疗的70例ACS患者为研究对象。按照介入时间不同,将患者分为A、B、C三组。A组PCI介入治疗时间为发病后<24 h,B组PCI介入治疗时间为发病后24~72 h,C组PCI介入治疗时间为发病72 h后。比较三组患者的PCI成功率、术后血流TIMI分级改善率、术后胸痛的缓解情况,以及术中、术后并发症的发生率和住院天数。结果术后,A、B、C三组患者在PCI成功率、术后血流TIMI分级改善率和术后胸痛率方面比较差异无统计学意义(P>0.05)。术中,A组患者的不良心血管发生率为24.0%,明显高于B组的12.0%和C组的10.0%,差异有统计学意义(P<0.05)。A、B、C三组患者术后不良心血管发生率分别为12.0%、8.0%和10.0%,差异无统计学意义(P>0.05);C组患者的住院天数为(22.6±2.9) d,明显长于A组的(17±2.7) d和B组的(14±3.9) d,差异有统计学意义(P<0.05)。结论冠状动脉综合征患者在发病后24~72 h内进行PCI介入治疗,更加安全高效,值得在临床广泛推广。
Objective To study the effect of different percutaneous coronary intervention (PCI) time on the prognosis of patients with acute coronary syndrome (ACS).Methods A total of 70 patients with ACS were selected as the subjects,who underwent PCI in the Department of Cardiovascular Medicine at Lueyang People's Hospital from June 2013 to June 2017.According to the intervention time,the patients were divided into three groups: A,B and C.The time of PCI interventional therapy in group A was less than 24 hours after onset,that in group B was 24-72 hours after onset, and that in group C was 72 hours after onset.Comparison of three groups were explored on the change of PCI success rate,graded improvement rate of postoperative blood flow TIMI,postoperative chest pain relief,incidence of intraoperative, postoperative complications,hospitalization days.Results After operation,there was no significant difference in PCI success rate,postoperative blood flow TIMI grading improvement rate,and postoperative chest pain rate among the three groups (P>0.05).During the operation,the incidence of adverse cardiovascular disease in group A was 24.0%, which was significantly higher than 12.0% in group B and 10.0% in group C (P<0.05).The incidence of adverse cardiovascular events in patients with A,B,and C was 12.0%,8.0%,and 10.0%,respectively (P>0.05).The hospitalization day in group C was (22.6±2.9) d,which was significantly longer than (17±2.7) d in group A and (14±3.9) d in group B (P< 0.05).Conclusion Patients with coronary syndrome who undergo percutaneous coronary intervention (PCI) within 24 to 72 hours after onset is safer and more effective,which is worthy of widespread promotion in clinical practice.
作者
刘宝堂
敬永强
郭荫飞
LIU Bao-tang;JING Yong-qiang;GUO Yin-fei(Department of Cardiovascular Medicine,Lueyang People'sHospital,Hanzhong 724300,Shaanxi,CHINA)
出处
《海南医学》
CAS
2019年第8期970-972,共3页
Hainan Medical Journal