摘要
糖尿病视网膜病变(diabetic retinopathy,DR)是导致不可逆性眼盲的重要原因之一,DR发病与动脉粥样硬化密切相关,其治疗干预靶点成为当今研究的热点。脂蛋白相关磷脂酶A2(lipoproteinassociated phospholipase A2,Lp-PLA2)是一种新型炎症因子,与动脉粥样硬化及炎症反应等相关。了解Lp-PLA2与DR相关性研究现状可能为进一步研究DR治疗提供新的思路。
Diabetic retinopathy (DR) is one of the important causes of irreversible blindness. DR is closely related to atherosclerosis, and its therapeutic intervention target has become a hot topic in current research. Lipoproteinassociated phospholipase A2 (Lp-PLA2), as a new inflammation factor, is related to atherosclerosis and inflammatory response. Understanding the current correlation of Lp-PLA2 and DR may provide a novel option in future treatment of DR.
作者
李婷婷
谢晓竞
LI Tingting;XIE Xiaojing(Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China)
出处
《临床与病理杂志》
2019年第4期863-868,共6页
Journal of Clinical and Pathological Research
