摘要
目的:探讨大补元煎联合麻黄附子细辛汤治疗偏头痛急性发作期肾虚头痛证的疗效。方法:选取2015年5月～2017年12月本院收治的偏头痛急性发作期患者90例,随机分为治疗组和对照组均为45例。对照组口服苯甲酸利扎曲普坦片,治疗组在对照组基础上予大补元煎联合麻黄附子细辛汤内服治疗,治疗3个月。比较两组症状积分、每周头痛发作次数、每次头痛持续时间及不良反应发生情况。结果:治疗后,两组患者的中医症状积分均较治疗前显著降低(P<0.01),每周头痛发作次数和每次持续时间明显减少(P<0.01),且治疗组治疗后的中医症状积分显著低于对照组(P<0.01),每周头痛发作次数和每次持续时间均明显少于对照组(P<0.01);治疗组总有效率显著高于对照组(P<0.05),不良反应发生率显著低于对照组(P<0.05)。结结论论:在西医治疗基础上,加用大补元煎联合麻黄附子细辛汤治疗偏头痛急性发作期肾虚头痛证可明显改善患者症状,提高疗效,且不良反应少。
Objective:To Investigate the clinical efficacy of Dabu Yuanjian combined with Mahuang Fuzi Xixin decoction in treatment of migraine acute phase syndrome of kidney asthenia and headache.Method:From May 2015 to December 2017, 90 patients with acute migraine attack were randomly divided into control group and treatment group(45 cases each) according to random number table.Control group was treated with rizatriptan benzoate tablets orally 10 mg/time and bid.The treatment group was treated with Dabu Yuanjian combined with Mahuang Fuzi Xixin decoction based on control one(1 dose/d and bid).Course of both groups were for 3 months.Scores of clinical symptom,frequency of headache per week,and duration time of headache every time were compared for two groups.Incidence of adverse reaction was recored in both groups.Results:After treatment, the scores of TCM symptoms in both groups were significantly lower than those before treatment(P<0.01), and the times and duration of headache attacks per week were significantly decreased(P<0.01). The score of TCM syndrome in the treatment group was significantly lower than that in the control group(P<0.01). The times of headache attack and the time of each headache attack in the treatment group were significantly lower than those in the control group(P<0.01). The total effective rate in the treatment group was significantly higher than that in the control group(P<0.05), and the incidence of adverse reactions in the treatment group was significantly lower than that in the control group(P<0.05).Conclusion: On the basic treatment of western medicine,Dabu Yuanjian combined with Mahuang Fuzi Xixin decoction in treating migraine acute phase syndrome of kidney asthenia and headache can markedly improve the symptoms,increase their efficacy,decrese incidence of adverse reaction.
作者
杨赣军
张小强
孙弋
YANG Gan-jun;ZHANG Xiao-qiang;SUN Yi(Department of Medicine of Jinggangshan University, Jiangxi Jian 343009)
出处
《按摩与康复医学》
2019年第10期37-39,共3页
Chinese Manipulation and Rehabilitation Medicine
关键词
偏头痛
肾虚头痛证
大补元煎
麻黄附子细辛汤
症状积分
头痛发作次数
migraine
syndrome of kidney asthenia and headache
Dabu Yuanjian
Mahuang Fuzi Xixin decoction
Symptom score
number of headache episodes
