摘要
目的观察与分析乙肝孕产妇性激素和应激激素状态的变化情况。方法选取2016年3月至2017年10月解放军第三○二医院诊治的80例乙肝孕产妇为观察组,以同期的80例健康孕产妇为对照组。检测与比较两组孕产妇的血清性激素和应激激素水平,比较观察组中不同HBV DNA载量孕产妇的检测结果,同时以Logistic分析性激素和应激激素与乙肝孕产妇的关系。结果观察组孕产妇的血清E2和应激激素水平高于对照组,其他性激素水平低于对照组;观察组中不同HBV DNA载量孕产妇的检测结果比较,其差异均具有统计学意义(均P<0.05)。Logistic分析显示,性激素和应激激素与乙肝孕产妇的关系有密切的关系。结论乙肝孕产妇性激素和应激激素状态的波动明显,应当重视对孕产妇进行此方面的监测。
Objective To observe and analyze the change in sex hormones and stress hormones state of pregnant women with hepatitis B. Methods 80 pregnant women with hepatitis B in the 302 Hospital of People′s Liberation Army from March 2016 to October 2017 were selected as the observation group, and 80 healthy pregnant women at the same period were selected as the control group. The serum sex hormones and stress hormones levels of the two groups were detected and compared, and the detection results of patients with different HBV DNA loads in the observation group were compared. The relationship between sex hormones and stress hormones and pregnant women with hepatitis B was analyzed with Logistic analysis. Results The serum E2 and stress hormones levels of observation group were higher than those of control group while other sex hormones levels were lower than those of control group, all with statistically significant differences(all P<0.05). There was statistically significant difference in the detection results between patients with different HBV DNA loads in the observation group(P<0.05). According to the logistic analysis, the sex hormones and stress hormones all had close relationship with pregnant women with hepatitis B. Conclusions The fluctuation of sex hormones and stress hormones state in pregnant women with hepatitis B is obvious, so attention should be paid to the monitoring of these indexes of pregnant women.
作者
赵薇
刘小慧
李丹丹
于秀芳
王新华
周红英
ZHAO Wei;LIU Xiaohui;LI Dandan;YU Xiufang;WANG Xinhua;ZHOU Hongying(Department of Obstetrics and Gynecology,The 302 Hospital of People’s Liberation Army,Beijing 100039,China)
出处
《中国性科学》
2019年第4期101-104,共4页
Chinese Journal of Human Sexuality
关键词
乙肝
孕产妇
性激素状态
应激激素状态
Hepatitis B
Pregnant women
Sex hormones state
Stress hormones state
