摘要
卡波西型血管内皮瘤(kaposiform hemangioendothelioma, KHE)是一种罕见的具有局部侵袭性的血管肿瘤,好发于婴幼儿,常伴有卡梅现象(Kasabach-Merritt phenomenon, KMP)。KHE目前缺乏基于循证医学的治疗规范。西罗莫司因较好的疗效和安全性有望成为一线用药。本文就目前KHE诊疗进展作一综述。
Kaposiform hemangioendothelioma(KHE)is a rare vascular tumor with local invasiveness.It is found predominantly in infants and children,and often accompanied by the Kasabach-Merritt phenomenon(KMP).There is no evidence-based standard for KHE treatment yet.The sirolimus is expected to be the first-line drug due to its efficacy and safety.This article reviews the progress of the diagnosis and treatment of KHE.
作者
羊樟福
胡博
付佩尧
喻敏成
徐泱
YANG Zhang-fu;HU Bo;FU Pei-yao;YU Min-cheng;XU Yang(Department of Liver Surgery,Liver Cancer Institute,Zhongshan Hospital,Fudan University,Shanghai 200032)
出处
《中国临床医学》
2019年第2期286-291,共6页
Chinese Journal of Clinical Medicine
基金
国家自然科学基金(81572884)~~
关键词
卡波西型血管内皮瘤
卡梅现象
西罗莫司
脉管肿瘤
kaposiform hemangioendothelioma
Kasabach-Merritt phenomenon
sirolimus
vascular tumor
