摘要
目的:研究并探讨咖啡因联合水床治疗早产儿呼吸暂停的临床效果。方法:将60例早产儿呼吸暂停患儿纳入研究对象,所有患儿均按照计算机随机数字分组法分为两组,各30例。对照组患儿采取常规治疗,观察组患儿在常规治疗基础上加用咖啡因、水床治疗,比较两组患儿的临床疗效、呼吸暂停发作情况、氨茶碱给药时间、住院时间、动脉血气分析指标。结果:观察组患儿的总有效率达到96.67%,相比于对照组明显更高,差异有统计学意义(P<0.05);与对照组比较,观察组患儿的呼吸暂停发作次数明显减少,且其呼吸暂停单次持续时间明显缩短,差异有统计学意义(P<0.05);观察组患儿的氨茶碱给药时间、住院时间均短于对照组患儿,差异有统计学意义(P<0.05);治疗24 h后,两组患儿的PaO_2、PaCO_2均较治疗前显著改善,差异有统计学意义(P<0.05),而观察组治疗24 h的PaO_2、PaCO_2均优于对照组患儿,差异有统计学意义(P<0.05)。结论:采用咖啡因联合水床治疗早产儿呼吸暂停具有显著的临床疗效,不仅可以有效缩短患儿治疗时间,缓解呼吸暂停症状,还可有效改善患儿动脉血气状况,减少支气管肺发育不良(bronchopulmonary dysplasia,BPD)的发生。
Objective To study and to explore the caffeine joint water bed clinical effect for the treatment of premature infant apnea.Method 60 cases of premature infant apnea children were enrolled in the research object,all children were grouped on the computer random number method,they were divided into two groups,30 cases in each group,control group of children were treated with regular treatment,observation group of children on the basis of conventional treatment combined with caffeine,water bed treatment,comparison of the clinical efficacy of two groups of children,apnea episodes,aminophylline dosage time,length of hospital stay,arterial blood gas analysis index.Results Observation group with total effective 96.67%,compared with the control group was significantly higher (P<0.05);Compared with the control group,observation group with apnea episodes of decreased significantly,and the duration of apnea single significantly shortened (P<0.05);The observation group with aminophylline dosage time,length of hospital stay were shorter than the control group patients (P<0.05);24 h after treatment,two groups of children with PaO2,PaCO2 than before treatment significantly improved (P<0.05),and the treatment group of 24 h PaO2,PaCO2 children was better than that of control group (P<0.05).Conclusion Using caffeine combined water bed treatment of premature apnea with remarkable clinical curative effect,can effectively shorten the treatment time,children not only alleviate symptoms of apnea,also can effectively improve children with arterial blood gas,reducing bronchial pulmonary dysplasia (bronchopulmonary dysplasia,BPD).
作者
左君
ZUO Jun(The People's Hospital of Dongxing District,Neijiang City,Neijiang 641100,China)
出处
《吉林医学》
CAS
2019年第5期968-970,共3页
Jilin Medical Journal
关键词
早产儿
呼吸暂停
咖啡因
水床
Preterm infants
Apnea
Caffeine
Water bed
