摘要
目的探讨轻微型肝性脑病患者的临床特征、发病危险因素及中医证候特点。方法对2017年6月—2018年10月首都医科大学附属北京地坛医院中西医结合中心住院部收治的120例肝硬化患者的临床资料进行分析,并对患者的中医证候特征进行研究。结果轻微型肝性脑病患者52例,占43.3%,其中男32例,女20例;非轻微型肝性脑病患者68例,占56.7%,其中男41例,女27例。与非轻微型肝性脑病组比较,轻微型肝性脑病组失代偿期患者明显增多(P<0.05),child分级明显增高(P<0.05),白蛋白水平明显降低(P<0.05)。经Logistic回归分析发现,白蛋白和child分级是轻微型肝性脑病发生的危险因素(P<0.05)。肝肾阴虚证和瘀血阻络证为轻微型肝性脑病患者的最主要证候。结论轻微型肝性脑病患者多发于肝硬化失代偿期,肝脏损害越严重,轻微型肝性脑病发生率越高。
Objective To explore the clinical features,risk factors and TCM syndromes of mild hepatic encephalopathy. Methods The clinical data of 120 patients with liver cirrhosis admitted to the inpatient department,Center for Integrative Medicine,Beijing Ditan Hospital affiliated to the Capital Medical University from June 2017 to October 2018 were analyzed,and the characteristics of TCM syndromes of were studied. Results There were 52 cases of mild hepatic encephalopathy,accounting for 43. 3%,among which there were 32 cases of male and 20 cases of female. 68 patients did not have mild hepatic encephalopathy,accounted for 56. 7%,including 41 male and 27 female cases. The patients with decompensated cirrhosis in the mild hepatic encephalopathy group were obviously increased than those in the non mild hepatic encephalopathy group( P < 0. 05),the child classification significantly higher( P < 0. 05),and albumin significantly decreased. With logistic regression analysis,albumin and the child classification were risk factors for mild hepatic encephalopathy occurrence( P < 0. 05). The syndrome of liver and kidney Yin deficiency and the syndrome of blood stasis in the collateral were the most important syndrome features of patients with mild hepatic encephalopathy. Conclusion Mild hepatic encephalopathy is mostly found in the stage of decompensated cirrhosis. The more severe liver damage is,the higher the incidence of mild hepatic encephalopathy is.
作者
姜婷婷
杨志云
江宇泳
王宪波
杨玉英
王融冰
JIANG Ting-ting;YANG Zhi-yun;JIANG Yu-Yong;WANG Xian-bo;YANG Yu-ying;WANG Rong-bing(Center for Integrative Medicine, Beijing Ditan Hospital Affiliated to the Capital Medical University, Beijing Institute of Infectious Diseases of Integrative Medicine, Key Department of Liver Disease of National Administration of Traditional Chinese Medicine, FamousDoctor Rong-bing Wang * s studio, Beijing 100015 , China)
出处
《北京中医药》
2019年第3期211-215,共5页
Beijing Journal of Traditional Chinese Medicine
基金
首都医科大学附属北京地坛医院青年人才发展基金"萌芽"支持计划项目(DTMY201611)
关键词
轻微型肝性脑病
危险因素
中医证候
minimal hepatic encephalopathy
risk factor
TCM syndrome
