摘要
目的探讨正念疗法联合帕罗西汀治疗对广泛性焦虑症患者睡眠的影响。方法选取我院2016年1月～2017年12月收治的广泛性焦虑症患者92例,采用数字随机表法将92例患者分为对照组及观察组,每组患者46例。对照组患者采用帕罗西汀治疗,观察组在对照组的基础上联合正念疗法治疗。比较两组患者临床疗效、睡眠功能及焦虑状态变化情况。结果观察组患者临床疗效总有效率明显优于对照组患者(93.47%vs 78.26%),差异具有统计学意义(P<0.05);两组患者治疗后6周PSQI量表总分与治疗前、治疗2周相比存在明显差异,呈逐渐下降的趋势(P<0.05);治疗2周后、治疗6周后,观察组患者PSQI量表总分明显低于对照组(P<0.05);治疗2周后、治疗6周后,观察组患者HAMA评分明显低于对照组(P<0.05)。结论正念疗法联合帕罗西汀治疗广泛性焦虑症临床疗效显著,可有效改善患者睡眠功能及焦虑状态。
Objective To investigate the effect of Mindfulness therapy combined with paroxetine in the treatment of patients with generalized anxiety disorder on sleep function. Methods 92 cases with generalized anxiety disorder were selected in our hospital from January 2016 to December 2017.92 patients were divided into control group and observation group by digital random table method with 46 patients in each group. The cases in the control group were treated by paroxetine,and the cases in the observation group were given with mindfulness therapy based on the treatment of the control group. The changes of clinical curative effect,sleep function and anxiety state were compared between the two group. Results The total curative rate in the observation group was significantly higher than that in the control group(93.47% vs 78.26%),and the difference was statistically significant(P<0.05). The scores of PSQI of two patients at 6 th weeks after treatment were significantly different with that before treatment and 2 th weeks after treatment with gradually decreased change(P<0.05). The PSQI score in the observation group 2 weeks after treatment,6 weeks after treatment were significantly lower than those in the control group(P<0.05). The HAMA score of observation group at 2 weeks after treatment and at 6 weeks after treatment were significantly lower than those in the control group(P<0.05). Conclusion The Mindfulness therapy combined with paroxetine in the treatment of patients with generalized anxiety disorder has good clinica efficacy,which can effectively improve patient sleep function and anxiety.
作者
贺建军
张晓莉
李雪萍
HE Jianjun;ZHANG Xiaoli;LI Xueping(Suining central hospital, Suining 629000, China)
出处
《国际精神病学杂志》
2019年第2期273-275,296,共4页
Journal Of International Psychiatry
关键词
正念疗法
帕罗西汀
广泛性焦虑症
睡眠功能
Mindfulness therapy
Paroxetine
Generalized anxiety disorder
Sleep function
