摘要
目的探讨心脑血管疾病危险因素差异,以指导心脑血管疾病的同防同治。方法连续收集解放军总医院2007年1月1日至12月31日首次发病的急性缺血性脑梗死和首次发病的急性缺血性冠心病患者资料。研究项目包括基线资料[年龄、性别、身高、体质量、体质指数、血压水平(舒张压、收缩压、平均动脉压)],危险因素(高血压、糖尿病、冠心病/心肌梗死、高脂血症、脑血管病史、吸烟史、饮酒史、家族史),脑梗死的TOAST分型。比较两组患者上述基线资料和危险因素的差异。结果总胆固醇、三酰甘油、载脂蛋白A1、低密度脂蛋白、糖化血清蛋白均差异有统计学意义(P <0. 05),脑血管病组均明显增高。logistic回归分析显示血压、糖代谢指标均为危险影响因素(P <0. 05),该两指标的水平在脑血管病组中明显增高。结论心脑血管疾病的主要危险因素大体相同,但存在差别。在控制好血脂的基础上,对于脑血管病更为严格的血压和血糖管理十分必要。
Objective To investigate the risk factor differences between cerebrovascular and cardiovascular disease in order to direct the prophylaxis and treatment strategies in common.Methods In this cross-sectional study,we reviewed the records of all consecutive acute cerebro-vascular and cardio-vascular disease patients who were treated at the PLA general hospital between January and December 2007.The following items were assessed:baseline data (including age,gender,height,weight,body mass index,blood pressure),risk factors (smoking,drinking,diabetes mellitus,hypertension,history of cardiovascular and cerebrovascular disease,serum lipids,apolipoproteins and homocysteine.Results The frequencies of serum total cholesterol,triglyceride,LDL cholesterol,apoa-1,Glycated serum protein level were significantly higher in the cerebrovascular patients’ group (P<0.05).In the logistic analysis,hypertension and hyperglycemia were positively associated with cerebrovascular patients (P<0.05).Conclusion Although main risk factors of cerebrovascular and cardiovascular disease are approximately identical,there are several differences in the details of the risk factors between cerebrovascular and cardiovascular disease.Based on blood lipid control,more strictly clinical strategies should be performed for the cerebrovascular patients to hypertension and blood glucose.
作者
张兴文
鱼喆
刘颖璐
苏慧
王岩
曹雅
何孜姿
杨梦丽
张绿明
于生元
Zhang Xingwen;Yu Zhe;Liu Yinglu;Su Hui;Wang Yan;Cao Ya;He Zizi;Yang Mengli;Zhang Lyuming;Yu Shengyuan(Department of Neurology,No.1 Medical Center of PLA General Hospital,Beijing 100700,China)
出处
《中国临床保健杂志》
CAS
2019年第3期292-297,共6页
Chinese Journal of Clinical Healthcare
基金
国家重点研发计划(2017YFC1307700)
中国人民解放军总医院医疗大数据研发项目(2016MBD-010)
关键词
心血管疾病
脑疾病
血脂异常
血压
血糖
Cardiovascular diseases
Brain diseases
Dyslipidemia
Blood pressure
Blood glucose
