摘要
目的探讨中药复方联合常规治疗对恶性肿瘤化疗期间骨髓抑制及细胞因子的影响。方法选取80例恶性肿瘤患者为研究对象,按照随机数字表法划分为对照组与观察组。对照组患者采取常规化疗+地榆升白片(中成药)治疗,观察组患者采取中药复方联合常规化疗。结果观察组患者与治疗组患者治疗后白细胞计数明显上升,组间数据差异有统计学意义(P <0. 05)。观察组患者治疗后,白细胞计数明显高于对照组。观察组与对照组患者第4次化疗前,红细胞(RBC)、血红蛋白(Hb)、血小板(PLT)水平降低,经治疗后观察组RBC、PLT、Hb水平更优(P <0. 05)。对照组患者治疗有效率为70. 0%,观察组患者治疗有效率为82. 5%,观察组优于对照组(P <0. 05)。结论中药复方联合化疗能够提高患者的白细胞计数,改善RBC、PLT、Hb水平。
Objective To analyze the effects of traditional Chinese medicine (TCM) combined with conventional therapy on bone marrow suppression and cytokines during chemotherapy of malignant tumors.Methods Eighty patients with malignant tumors in our hospital from August 2017 to January 2019 were enrolled in the study.Eighty patients were randomly divided into control group and observation group.The patients in the control group were treated with chemotherapy + Diyu Shengbai Tablet (Chinese medicine) and the patients in the observation group were treated with traditional Chinese medicine combined with chemotherapy.Results The white blood cells of the observation group and the treatment group were significantly increased after treatment.The difference was statistically significant between the groups (P<0.05).After treatment,the number of white blood cells was significantly higher in the observation group than that in the control group.The levels of RBC,PLT and Hb were lower in the observation group and the control group before the fourth chemotherapy.After treatment,the levels of RBC,PLT and Hb of the observation group were better.The effective rate of the control group was 70.0% and the effective rate of the observation group was 82.5%.The observation group was significantly better than the control group.Conclusion Traditional Chinese medicine combined with compound chemotherapy can increase the levels of WBC,RBC,PLT and HB and achieve the improvement of patient’ quality of life,and thus the patient’s survival is prolonged.
作者
徐媛媛
陶宋词
胡世莲
李金虎
徐腾云
Xu Yuanyuan;Tao Songci;Hu Shilian;Li Jinhu;Xu Tengyun(Department of TCM,the First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230001,China)
出处
《中国临床保健杂志》
CAS
2019年第3期349-352,共4页
Chinese Journal of Clinical Healthcare
基金
中央引导地方科技发展专项专业性技术创新平台项目(YDZX20183400002555
2017070503B041)
安徽省重点实验室绩效项目(1606c08236)
安徽省科技攻关项目(1501041142)
关键词
肿瘤
化放疗
细胞因子类
中草药
Neoplasms
Chemoradiotherapy
Cytokines
Drugs,Chinese herbal
