摘要
目的观察草酸艾司西酞普兰联合生物反馈—认知行为疗法治疗慢性主观性头晕的临床疗效。方法选取本院收治的慢性主观性头晕患者64例为研究对象,将64例患者随机分为对照组和研究组,每组各32例,两组患者均给予口服草酸艾司西酞普兰治疗,研究组在此基础上给予生物反馈—认知行为疗法进行干预治疗。比较两组患者治疗前及治疗后第2周、第4周、第8周眩晕残障程度评定量表评分结果变化及临床疗效。结果与治疗前比较,两组患者治疗后第2周、第4周、第8周DHI评分明显降低,差异具有统计学意义(P<0.05);与治疗后第2周比较,两组患者治疗后第4周、第8周的DHI评分明显降低,差异具有统计学意义(P<0.05);与治疗后第4周比较,两组患者治疗后第8周DHI评分明显降低,差异具有统计学意义(P<0.05)。与对照组治疗前比较,研究组治疗前DHI评分未见明显变化,差异无统计学意义。分别与对照组治疗后第2周、第4周、第8周比较,研究组治疗后第2周、第4周、第8周DHI明显降低,差异具有统计学意义(P<0.05)。研究组患者总有效率(96.88%)明显高于对照组总有效率(78.14%),差异具有统计学意义(x^2=5.148,P<0.05)。结论草酸艾司西酞普兰联合生物反馈—认知行为疗法治疗慢性主观性头晕临床疗效显著,头晕症状改善明显,安全可靠,值得临床借鉴应用。
Objective To observe the clinical efficacy of escitalopram oxalate combined with biofeedback-cognitive behavioral therapy in the treatment of chronic subjective dizziness.Methods 64 patients with chronic subjective dizziness admitted to our hospital were selected as the research object.64 patients were randomly divided into control group and research group,32 cases in each group.Both groups were given oral escitalopram oxalate,and the research group was given biofeedback-cognitive behavioral therapy to intervene on this basis.The changes of vertigo and disability scale scores and clinical efficacy were compared between the two groups before treatment and at the 2nd,4th and 8th weeks after treatment. Results Compared with before treatment,the DHI scores of the two groups were significantly lower in the 2nd,4th and 8th week after treatment (P<0.05).Compared with the 2nd week after treatment,the DHI scores of the two groups were significantly lower in the 4th and 8th week after treatment (P<0.05).Compared with the 4th week after treatment,the DHI scores of the two groups were significantly lower in the 8th week after treatment (P<0.05).The difference was statistically significant (P< 0.05).Compared with the control group before treatment,there was no significant change in DHI score before treatment in the study group,and there was no significant difference between the two groups.Compared with the control group in the 2nd,4th and 8th weeks after treatment,DHI in the study group decreased significantly in the 2nd,4th and 8th weeks after treatment (P< 0.05).The total effective rate of the study group (96.88%) was significantly higher than that of the control group (78.14%).The difference was statistically significant (χ^2 =5.148,P<0.05).Conclusion Escitalopram oxalate combined with biofeedback-cognitive behavioral therapy is effective in treating chronic subjective dizziness.The symptoms of dizziness are improved obviously,safe and reliable,which is worthy of clinical reference and application.
作者
周瑞泽
杨利勇
赖小梅
Zhou Ruize;Yang Liyong;Lai Xiaomei(Department of Neurology,People's Hospital of Ruijin,Ruijin,Jiangxi,342500,China;ICU,Traditional Chinese Medicine Hospital of Ruijin,Ruijin,Jiangxi,342500,China)
出处
《当代医学》
2019年第15期106-109,共4页
Contemporary Medicine
