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利多卡因联合肝素与地塞米松防治断指再植术后血管危象的作用分析 被引量:6

Analysis of the role of lidocaine combined with heparin and dexamethasone in preventing and treating vascular crisis after replantation of severed fingers
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摘要 目的探讨利多卡因、肝素和地塞米松防治断指再植术后血管危象的作用。方法对本院特定时段内接诊的20例行断指再植术患者展开研究,按照麻醉措施的差异,将其以1∶1的比例分为两组,给予肝素+罂粟碱治疗的为对照组,给予利多卡因+肝素+地塞米松治疗的为观察组,对比疼痛评分、血管危象、C反应蛋白CRP、心率HR、平均动脉压MAP、血氧饱和度SpO_2。结果观察组术后3 h、术后8 h、术后12 h、术后48 h VSA评分均高于对照组,组间对比,差异具有统计学意义(P<0.05),观察组总疗效为100.0%,对照组为60.0%,组间对比差异具有统计学意义(P<0.05),观察组CRP组间比较差异具有统计学意义(P<0.05)。结论在断指再植术患者的临床治疗过程中给予利多卡因+肝素+地塞米松治疗值得推广。 Objective To investigate the role of lidocaine,heparin and dexamethasone in preventing and treating vascular crisis after replantation of severed fingers.Methods Twenty patients undergoing replantation of severed fingers during a specific period of time in our hospital were studied. According to the difference of anesthesia measures,they were divided into two groups according to the ratio of 1:1.The treatment with heparin + papaverine was in the control group,lidocaine + heparin + dexamethasone was given as the observation group,and the pain score,vascular crisis,Creactive protein CRP,heart rate HR,mean arterial pressure MAP,and blood oxygen saturation SpO2 were compared.Results The VSA scores of the observation group were higher than those of the control group at 3 h,8 h,12 h and 48 h after operation.The difference was statistically significant (P<0.05).The total effect of the observation group was 100.0%,the total effect of the control group was 60.0%,the difference between the groups was statistically significant (P<0.05),and the CRP index of the observation group was statistically significant (P<0.05).Conclusion The treatment of lidocaine + heparin + dexamethasone in the clinical treatment of patients undergoing replantation of the severed fingers is worthy of promotion.
作者 温财春 林清惠 陈高烨 Wen Caichun;Lin Qinghui;Chen Gaoye(Zhangzhou Zhengxing hospital,Zhangzhou,Fujian,363000,China)
机构地区 漳州正兴医院
出处 《当代医学》 2019年第15期116-118,共3页 Contemporary Medicine
关键词 利多卡因 肝素 地塞米松 断指再植术 血管危象 作用分析 Lidocaine Heparin Dexamethasone Replantation of severedfingers Vascular crisis Role analysis
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