摘要
目的建立红外光谱法快速鉴别大黄不同炮制品配方颗粒的方法。方法采用红外光谱结合二阶导数光谱及二维相关光谱法分析不同炮制品配方颗粒光谱特征。结果二阶导数光谱在1200～1800/cm范围内差异较大,二维相关光谱图差异明显。结论通过比较不同炮制品红外光谱图、二阶导数光谱图及二维相关光谱图,可以准确、快速鉴别大黄不同炮制品配方颗粒。
OBJECTIVE To establish a rapid FTIR method for identifying of different processed products of Rhubarb Formula Granules.METHODS Different processed products of Rhubarb Formula Granules were researched by infrared、second derivative spectra and two-dimensional correlation spectroscopy.RESULTS In second derivative spectra,the intensity,shape and position of the peaks were different in the range of 1200~1800/cm,Two-dimensional correlation spectroscopy were obvious difference.CONCLUSION By comparing the infrared spectra、second derivative spectra and two-dimensional correlation spectroscopy of different processed products,It can be identified rapidly and accurately of different processed products of Rhubarb Formula Granules.
作者
霍保军
田方
李军山
彭新华
张肖建
高晗
李振江
HUO Bao-jun;TIAN Fang;LI Jun-shan;ENG Xin-hua;ZHANG Xiao-jian;GAO Han;LI Zhen-jiang(Shineway Pharmaceutical Group Ltd.,Shijiazhuang 051430,China;TCM Formula Granule Engineering Technology Research Center of Hebei,Shijiazhuang 050200,China)
出处
《海峡药学》
2019年第4期53-56,共4页
Strait Pharmaceutical Journal
基金
国家中医药管理局中医药科学技术研究专项课题(国中医药科2013X07)
河北省科技计划项目(14272504D)
关键词
红外光谱法
导数光谱
二维光谱
大黄
配方颗粒
Infrared spectrum
Second derivative spectrum
Two-dimensional correlation pectroscopy
Rhubarb
Formula Granules
