摘要
目的比较聚乙烯醇颗粒(PVA)、Glubran胶以及Glubran+碘油术前栓塞治疗颅内富血运脑膜瘤的疗效。方法选取2013年6月—2018年1月南方医科大学第三附属医院神经外科收治的颅内富血运脑膜瘤患者86例为研究对象,根据随机数字表法分为A组(33例,采用PVA进行填充)、B组(26例,采用Glubran胶进行填充)及C组(27例,采用Glubran+碘油填充),比较各组栓塞术的效果,并观察记录手术时间、术中出血量、记录住院天数、术后住院天数、总费用,观察并发症发生情况。结果栓塞术疗效比较C组>B组>A组,差异均有统计学意义(Z=43. 830,P=0. 000)。手术时间A组> B组> C组,差异均有统计学意义(F=55. 577, P=0. 000)。3组患者术中总出血量、住院天数、术后住院天数、总费用、并发症发生率比较差异均无统计学意义(F/P=1. 138/0. 325、1.474/0. 235、0. 331/0.719、2. 059/0.134,χ~2/P=1. 118/0. 572)。结论富血运脑膜瘤患者采用Glubran+碘油进行术前栓塞能让栓塞剂在肿瘤内更好地弥散,可缩短手术时间,给手术带来更大的益处。
Objective To compare the efficacy of preoperative embolization with polyvinyl alcohol granules(PVA),Glubran glue and Glubran + lipiodol in the treatment of intracranial hypervascular meningiomas. Methods From June 2013 to January 2018, 86 patients with intracranial blood-rich meningiomas admitted to the Department of Neurosurgery, Third Affiliated Hospital of Southern Medical University were selected as the subjects. They were randomly divided into group A(33 cases filled with PVA), group B(26 cases filled with Glubran glue) and group C(27 cases filled with Glubran + iodine oil).The effects of embolization were compared and observed. The operation time, intraoperative bleeding volume, hospitalization days, postoperative hospitalization days and total cost were recorded, and the occurrence of complications was observed. Results The curative effect of embolization was compared between group C > group B > group A, and the difference was statistically significant(Z =43. 830, P = 0. 000). The operation time was group A > group B > group C, the difference was statistically significant(F = 55.571, P =0.000). There were no significant differences in the total amount of intraoperative blood loss, hospital stay, postoperative hospital stay, total cost, and complication rate between the three groups(F/P= 1. 138/0.325, F/P = 1.474/0.235, F/P = 0. 331/0.719,F/P = 2. 059/0. 134,χ~2/P = 1. 118/0. 572). Conclusion Preoperative embolization with Glubran and lipiodol in patients with hypervascularized meningioma can make the embolic agent diffuse better in the tumor, shorten the operation time and bring greater benefits to the operation.
作者
黄伟佳
黄理金
陈锦华
张晓斌
刘铁坚
HUANG Weijia;HUANG Lijin;CHEN Jinhua;ZHANG Xiaobin;LIU Tiejian(Department of Neurosurgery,The Third Affiliated Hospital of Southern Medical University,Guangdong Province,Guangzhou 510515,China)
出处
《疑难病杂志》
CAS
2019年第5期442-445,共4页
Chinese Journal of Difficult and Complicated Cases
基金
广东省自筹经费类科技计划项目(2201500229)
关键词
富血运脑膜瘤
介入手术
栓塞材料
疗效
Hypervascularized meningioma
Interventional therapy
Embolic materials
Therapeutic effect
