摘要
骨肉瘤是一种常见于青少年的原发性恶性骨肿瘤,具有极高的转移性、侵袭性、致死性。骨肉瘤的早期诊断与治疗一直是骨科领域的一个研究热点。但目前对于骨肉瘤不良预后相关基因的研究不够透彻,以至于骨肉瘤患者的生存改善情况一直维系在一个瓶颈期。本文将对目前骨肉瘤不良预后相关基因的研究进展作一综述,以期为骨肉瘤早期诊断与治疗的进一步研究提供一定的基础资料,以改善骨肉瘤患者的不良预后。
Osteosarcoma is a common malignant bone tumor in adolescents. It has extremely metastasis, invasion and mortality. The early diagnosis and treatment of osteosarcoma has been a research hotspot. However, related genes of poor prognosis of osteosarcoma are still unclear in present, and the survival improvement of osteosarcoma patients has maintained in a bottleneck period. In order to provide baseline data for the early diagnosis and treatment of osteosarcoma, we summarized genes related to poor prognosis of osteosarcoma.
作者
黄镇
李晓东
黄庆山
林建华
HUANG Zhen;LI Xiaodong;HUANG Qingshan;LIN Jianhua(Department of Orthopedics, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005 China)
出处
《中华骨与关节外科杂志》
2019年第3期236-240,共5页
Chinese Journal of Bone and Joint Surgery
基金
国家自然科学基金(31571292)
关键词
骨肉瘤
不良预后
基因
Osteosarcoma
Poor Prognosis
Gene
