摘要
目的回顾性分析2012年-2017年医院门诊和住院就诊者丙型肝炎病毒抗体(HCV)的检测阳性率,了解其感染的流行趋势。方法收集2012年-2017年212684例血清标本,HCV采用酶联免疫吸附试验(ELISA)进行检测,分析HCV在调查人群、不同年龄、性别组和不同来源中的阳性率。结果2012年-2017年,调查人群HCV总阳性率为0.21%,HCV检测例数与HCV阳性率呈同步先升后降的趋势;不同性别组,男性感染率为0.25%,女性感染率为0.17%,差异有统计学意义(P<0.05);在不同年龄段分组中,随着年龄的增长,HCV阳性率呈先升后降的趋势,30岁~60岁阳性率最高,为0.26%,HCV阳性率在各年龄段差异有统计学意义(P<0.05);HCV阳性患者中,肾内科阳性率最高,为77.4%,各科室HCV阳性率差异有统计学意义(P<0.05)。结论宁波地区HCV在年龄和性别组间有差异,男性高于女性,中青年是HCV感染的高发期,肾内科发现较多丙肝患者,应进一步加强对血透患者丙肝阳性率的检测,控制和减少交叉感染。
Objective To retrospectively analyze the serologic tests of hepatitis C virus ( HCV) from outpatients and inpatients in Li Huili Hospital, so as to understand the epidemic trend of the infections. Methods 212 684 blood specimens were collected from 2012 to 2017, and the positive rate of HCV in crowd, different ages, different sexes and different specimen sources were detected. HCV was detected by using enzyme - link immunosorbent assay ( ELISA). Results The total positive rate of HCV was 0. 21%. The cases of HCV testing and the positive rate of HCV first increased and then decreased. The cases were mainly distributed in men ( 0. 25%) and women ( 0. 17%), and there was statistical significance on the difference among different gender groups ( P < 0. 05). The positive rate of HCV first increased and then decreased with the growth of age. Patients aged between 30 and 60 had the highest positive rate of HCV, and the differences were statistically significant in different age groups ( P < 0. 05). Conclusion The positive rate of HCV is different in gender and age groups in Ningbo area. The middle - aged has a high incidence of HCV infection. The department of nephrology finds more cases of HCV, and HCV test should be further strengthened in hemodialysis patients, so as to control and reduce the spread of cross infection.
作者
丁毅
穆银玉
金雨虹
DING Yi;MU Yin-yu;JIN Yu-hong(ICU, Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang 315040, China)
出处
《中国卫生检验杂志》
CAS
2019年第10期1273-1274,1277,共3页
Chinese Journal of Health Laboratory Technology
