摘要
目的分析流产后不同间隔再次妊娠对妊娠结局的影响,探讨流产后再次妊娠的合理时间。方法采用回顾性分析方法,选择2016年2月至2018年2月于我院妇产科门诊就诊且本次妊娠前有流产史孕妇198例,根据上次流产时间距本次妊娠末次月经时间分为短期组(间隔小于3个月)31例、中期组(间隔3～6个月)48例、长期组(间隔6～24个月)55例和超长期组(间隔24个月以上)64例,四组孕妇均在我院妇科门诊定期随诊至此次妊娠结束,比较四组孕妇妊娠结局、妊娠并发症、婴儿结局。结果中期组、长期组、超长期组足月产率显著高于短期组(P<0.05),早产率、流产率显著低于短期组(P<0.05),且超长期组、长期组、中期组足月产率、再次妊娠早产比率、流产率三组无统计学差异(P>0.05);四组异位妊娠率无统计学差异(P>0.05);短期组出现1例宫内死胎,其余组别均无宫内死胎出现;中期组、长期组、超长期组并发症总发生率显著低于短期组(P<0.05);足月正常新生儿比率显著高于短期组(P<0.05);低体重儿比率显著低于短期组(P<0.05);四组间巨大儿比率、畸形儿比率、新生儿Apgar评分无统计学差异(P>0.05)。结论流产后再次妊娠需至少间隔3个月,以保证妇女身心恢复,在无严重流产并发症且机体恢复较好的情况下,不必刻意延长再次妊娠间隔时间。
Objective To analyze the effect of re-pregnancy at different intervals after abortion on pregnancy outcomes and explore the reasonable time for re-pregnancy after abortion.Methods A retrospective analysis was performed in 198 pregnant women with history of abortion before re-pregnancy who were treated in the Department of Obstetrics and Gynecology of the hospital from February 2016 to February 2018 were selected.According to the time from the last abortion to the last menstruation before re-pregnancy,the subjects were divided into short-term group(interval shorter than 3 months,31 cases),medium-term group(interval between 3 and 6 months,48 cases),long-term group(interval between 6 and 24 months,55 cases)and super long-term group(interval longer than 24 months,64 cases).All of the pregnant women were regularly followed up till the end of the pregnancy.The pregnancy outcomes,pregnancy complications and infant outcomes were compared among the four groups.Results The full-term delivery rate of the mid-term group,long-term group or super long-term group was significantly higher than that of the short-term group(P<0.05),while the premature delivery rate and abortion rate were significantly lower than those of the short-term group(P<0.05),without statistically significant difference among the super long-term group,long-term group and medium-term group(P>0.05).There was no significant difference in the ectopic pregnancy rate among the four groups(P>0.05).There was one case of intrauterine fetal death in the short-term group but none in the other groups.The overall incidence of complications in the medium-term group,long-term group or super long-term group was significantly lower than that in the short-term group(P<0.05),while the proportion of normal neonates was significantly higher than that in the short-term group(P<0.05).There was no significant difference in rates of macrosomia and deformed baby or neonatal Apgar scores among the four groups(P>0.05).Conclusion The time from last abortion to re-pregnancy should be at least three months to ensure the physical and mental recovery of women.Under the condition that there are no severe abortion complications and the body recovers well,it is not necessary to deliberately prolong the interval to re-pregnancy.
作者
曾丽萍
Zeng Liping(Obstetrics and Gynecology,Southern Medical University Affiliated Xiaolan Hospital,Zhongshan 528415,China)
出处
《哈尔滨医药》
2019年第2期123-126,共4页
Harbin Medical Journal
基金
广东省中山市医学科研项目<流产后不同间隔再次妊娠和妊娠结局关系>(2016A020273)
关键词
流产
时间间隔
再次妊娠
妊娠结局
Abortion
Time interval
Second pregnancy
Pregnancy outcome
