摘要
目的:检测尖锐湿疣(CA)初发患者皮损及正常包皮组织中Livin和Caspase-3的表达。方法:采用免疫组化法检测Livin和Caspase-3在30例CA初发患者皮损和20例正常包皮组织中的表达。结果:Livin和Caspase-3在CA组织的阳性表达率分别为76.67%和43.33%,在正常包皮组织表达率分别为25.00%和70.00%。Livin与Caspase-3在CA组织中的表达强度之间无相关性(r=0.238,P>0.05)。结论:在CA初发患者皮损中存在Livin高表达和Caspase-3低表达,二者可能共同参与了CA的发生与发展。
Objective:To determine the expression of Livin and Caspase-3 in the lesions of incipient condyloma acuminatum. Methods:The expression of Livin and Caspase-3 in the lesions of incipient condyloma acuminatum and normal prepuce tissues was detected by Streptavidin-peroxidase. Results:The positivity rates of Livin and Caspase-3 in the incipient condyloma acuminatum and normal prepuce were 76.67% and 43.33%, 25.00% and 70.00%. There was no correlation between the expression intensity of Livin and Caspase-3 in the incipient condyloma acuminatum group ( r=0.238,P >0.05). Conclusion:There is high expression of Livin and low expression of Caspase-3 in the lesions of incipient condyloma acuminatum. Both may be involved in the development of condyloma acuminatum.
作者
林丽
王军
秦晓明
LIN Li;WANG Jun;QIN Xiaoming(Department of Dermatology and STD,The Second Affiliated Hospital of Wannan Medical College,Wuhu 241001,China;Department of Dermatology and STD,The First Affiliated Hospital of Wannan Medical College,Wuhu 241001,China)
出处
《中国麻风皮肤病杂志》
2019年第6期338-341,共4页
China Journal of Leprosy and Skin Diseases
基金
皖南医学院重点科研项目培育基金(编号:WK2018ZF08)
