摘要
目的:探索普拉克索治疗帕金森病用药效果。方法:选取2017年3月22日-2018年3月22日笔者所在医院收治的帕金森病患者100例,将其按奇偶数法分为两组,对照组的50例患者进行美多芭片治疗,观察组的50例患者进行普拉克索治疗。结果:观察组患者的便秘率(2.00%)、尿频尿急率(4.00%)、睡眠障碍率(4.00%)、感觉异常率(2.00%)、不良反应反应率(4.00%)、MMSE评分(28.42±1.39)分、UPDRS评分(15.86±1.86)分、10 m折返步行时间(10.29±2.86)s、转弯时间(3.05±0.29)s、起立时间(2.38±1.23)s均优于对照组(P<0.05)。结论:对帕金森病患者实施普拉克索治疗效果显著,可提高用药安全性。
Objective:To explore the effect of Pramipexole in the treatment of Parkinson disease.Method:A total of 100 patients with Parkinson disease admitted in our hospital from March 22nd,2017 to March 22nd,2018 were selected.They were divided into two groups according to the odd and even number method.50 patients in the control group were treated with Madob Tablets,and 50 patients in the observation group were treated with Pramipexole.Result:The constipation rate(2.00%),urinary frequency urgency rate(4.00%),sleep disturbance rate(4.00%),sensory abnormality rate(2.00%),adverse reaction rate(4.00%),and MMSE score(28.42±1.39)points,UPDRS score(15.86±1.86)points,10 m reentry walking time(10.29±2.86)s,turning time(3.05±0.29)s,and standing time(2.38±1.23)s in the observation group were better than those in the control group(P<0.05).Conclusion:The effect of Pramipexole on patients with Parkinson disease is remarkable,which can improve the safety of medication.
作者
李宏毅
张敏
LI Hongyi;ZHANG Min(Wuhan No.Nine Hospital,Wuhan 430080,China)
出处
《中外医学研究》
2019年第13期50-52,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
