摘要
研究测定消痹膏中欧前胡素含量限度的方法。通过高效液相色谱法测定消痹膏中欧前胡素的含量,并确定其含量限度。欧前胡素的峰面积浓度范围为5.84~58.4μg/mL,与进样量呈良好的线性关系。平均加样回收率为97.57%,RSD%=1.45%(n=6)。通过三批消痹膏样品确定其制剂中欧前胡素的平均含量为0.156mg/g。该方法灵敏度高,重复性好,专属性高,可为消痹膏制剂质量标准的制定提供依据。
A method for determination of the content limitation of imperatorin in Xiao Bi Ointment was established.The content of imperatorin was determinated by HPLC,and the content limitation of Xiao Bi Ointment was decided.The experiment showed a good linear relationship at the ranges of 5.84~58.4μg/mL.The average recovery rate was 97.57%,and RSD was 1.45%(n=6).The content limitation of imperatorin was determined at 0.156 mg/g.The method has high sensitivity,good repeatability and high specificity,and it can provide a basis for the formulation of quality standards of Xiao Bi Ointment.
作者
刘国彬
LIU Guo-bin(Traditional Chinese hospital of Lu an,Anhui Lu an 237000,China)
出处
《广州化工》
CAS
2019年第10期85-86,99,共3页
GuangZhou Chemical Industry
基金
安徽省卫生计生委中医药科研课题(No:2016zy44)
