摘要
多囊卵巢综合征(polycystic ovary syndrome,PCOS)是育龄期女性最常见的内分泌及代谢紊乱性疾病之一,但其发病机制尚不明确。目前大多数研究认为,胰岛素抵抗、高雄激素血症、神经内分泌、炎症等因素在PCOS发病过程中起重要作用。PCOS同时也是女性不孕的重要原因之一。对于PCOS合并不孕,促排卵治疗是其助孕的重要手段。为此本文对PCOS排卵障碍及促排卵治疗的研究进展做一综述,探讨促排卵治疗在PCOS合并不孕中的作用。
Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age, but the pathogenesis is still unknown. At present, most studies suggest that insulin resistance, hyperandrogenism, neuroendocrine and inflammatory factors play important roles in the pathogenesis of PCOS. PCOS-related anovulation is an important reason of female infertility. For PCOS with infertility, ovulation induction is an essential method to assisted reproduction. Therefore, we reviewed the development of the studies of PCOS-related anovulation and ovulation induction therapy, and discussed the role of ovulation induction therapy for PCOS with infertility.
作者
甘文锦
李刚
Gan Wenjin;Li Gang(Hainan Provincial Key Laboratory of Tropical Medicine, Hainan Medical College, Haikou 571101, China;Reproductive Medical Center, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China)
出处
《中华生殖与避孕杂志》
CAS
CSCD
北大核心
2019年第4期322-324,共3页
Chinese Journal of Reproduction and Contraception
基金
国家自然科学基金(81771534).
关键词
多囊卵巢综合征
排卵障碍
促排卵
Polycystic ovary syndrome
Ovulation failure
Ovulation induction
