摘要
采用文献检索和临床病例,探讨泌尿系统肿瘤的病因学分析,明确影响因素。泌尿系统肿瘤的发病原因包含内因(遗传和突变)和外因(环境、吸烟、辐射等);涵盖所有7个致病原因(物理因素、化学因素、生物学因素、遗传因素、内分泌因素、免疫功能和精神因素);覆盖泌尿系统所有6个解剖部位(6/6,100%),10个统计病种(10/15,66.67%)。其中,吸烟、咖啡、茶和职业因素等为可能的致病原因。对于尿路上皮癌,医源性因素、慢性感染和下尿路梗阻也是可能致病因素。有3种泌尿系肿瘤可以预防,大部分疾病具有遗传和基因异常可能。泌尿系统肿瘤的病因覆盖所有致病因素,病因学研究可以为临床诊治提供依据。防患于未然,预防是关键。
We reviewed through literature search and data analysis, the specific etiology and causes of urological tumors.The etiology of urological tumors includes internal causes(heredity and variation) and external causes(environment, smoking, radiation, etc.), covering all 7 causes(physical, chemical, biological, genetic, endocrine, immune and mental factors);covering all 6 dissections of the urinary system(6/6,100%) and 10 statistical diseases(10/15, 66.67%). Among them, smoking, coffee, tea and occupational factors are possible risk factors.The causes of urothelial carcinoma include iatrogenic factors chronic infection and lower urinary tract obstruction are possible risk factor. Some diseases can be prevented. The etiology of urologic tumors covers all pathogenic factors, and etiological research can provide evidence for clinical diagnosis and treatment. Prevention is the key.
作者
董德鑫
李汉忠
纪志刚
石冰冰
DONG De-xin;LI Han-zhong;JI Zhi-gang;SHI Bing-bing(Department of Urology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences &Peking Union Medical College,Beijing 100730,China)
出处
《基础医学与临床》
CSCD
2019年第6期904-907,共4页
Basic and Clinical Medicine
关键词
泌尿系统肿瘤
病因
诱因
预防
urinary neoplasms
etiology
inducement
prevention
