摘要
选择了药典收载的4种淫羊藿与巫山淫羊藿药材共5个物种33份样品,比较不同加热处理导致的淫羊藿苷含量的变化,结果表明淫羊藿药材或粉末150℃加热处理30 min是适宜的处理方法,淫羊藿苷的增加量最大,但该条件并不能将前体化合物3’’’-羰基-2″-β-L-喹诺糖基淫羊藿苷(3’’’-carbonyl-2″-β-L-quinovosyl icariin,CQICA)全部转化为淫羊藿苷,且同时淫羊藿苷也有部分降解。在来自5个物种药材中,朝鲜淫羊藿的淫羊藿苷增加量较大,一般增加1～3倍,心叶淫羊藿和柔毛淫羊藿一般也有增加,但增加幅度不同样品差别很大,箭叶淫羊藿和巫山淫羊藿则少有增加,或稍微有所降低。
The change of icariin( ICA) content in thirty-three samples of five Epimedium species listed in the Chinese Pharmacopoeia( 2015 edition),including E. brevicornu,E. sagittatum,E. pubescens,E. koreanum,and E. wushanense has been investigated in this study. The results indicated that the optimized process procedure was baking at 150 ℃ for 30 min,and 3′′′-carbonyl-2″-β-L-quinovosyl icariin( CQICA) could not be translated into ICA and ICA could be converted under this heating process condition. ICA increased remarkably after the heating process by 1-3 times in E. brevicornu,E. wushanense and E. koreanum,and increased lightly in E. brevicornum and E. pubescens,while ICA slightly increased or decreased in E. sagittatum and E. wushanense.
作者
孙欣光
周茗
马百平
郭宝林
SUN Xin-guang;ZHOU Ming;MA Bai-ping;GUO Bao-lin(Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences,Peking Union Medical College,Beijing 100193,China;Institute of Radiation Medicine,Academy of Millitary Medical Sciences,Beijing 100850,China)
出处
《中国中药杂志》
CAS
CSCD
北大核心
2019年第9期1857-1861,共5页
China Journal of Chinese Materia Medica
基金
国家自然科学基金项目(81473302)
中国医学科学院医学与健康科技创新工程项目(2017-I2M-3-013)
