摘要
[目的]观察玉屏风胶囊联合西药治疗慢性湿疹(卫表不固)疗效。[方法]使用随机平行对照方法,将77例患者按就诊顺序号抽签随机分为两组。对照组38例氯雷他定,10mg/次,1次/d,睡前服用;复方氟米松软膏,适量涂于患处,并缓慢按揉,早晚各一次。治疗组39例玉屏风胶囊,1g/次,3次/d;西药治疗同对照组。连续治疗7d为1疗程。观测临床表现、白介素-10、白介素-2、血清免疫球蛋白E、不良反应。连续治疗3疗程(21d),判定疗效。[结果]治疗组痊愈30例,显效6例,有效2例,无效1例,总有效率97.43%;对照组痊愈17例,显效10例,有效5例,无效6例,总有效率84.21%;治疗组疗效优于对照组(P<0.05)。IL-10、IL-2、IgE两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]玉屏风胶囊联合西药治疗慢性湿疹(卫表不固),疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Yupingfeng capsule combined with western medicine on chronic eczema.[Method] 77 patients were randomly divided into two groups by drawing lots according to the order of visiting. In the control group, 38 patients were given loratadine 10 mg/time, once a day, before going to bed. Compound flumethasone ointment was applied to the affected area in a proper amount and kneaded slowly, once in the morning and once in the evening. 39 cases in the treatment group were treated with Yupingfeng capsule, 1 g/time, 3 times/day, while the control group was treated with western medicine.Continuous treatment for 7 days is a course of treatment. Clinical manifestations, interleukin-10, serum immunoglobulin E and adverse reactions were observed. Continuous treatment for 3 courses(21 days) to determine the efficacy.[Result] In the treatment group, 30 cases were cured, 6 cases were markedly effective,2 cases were effective and 1 case was ineffective, the total effective rate was 97.43%. In the control group, 17 cases were cured, 10 cases were markedly effective, 5 cases were effective and 6 cases were ineffective, the total effective rate was 84.21%. The curative effect of the treatment group was better than that of the control group(P<0.05). IL-10, IL-2 and IgE were improved in both groups(P<0.01), and the improvement in treatment group was better than that in control group(P<0.01).[Conclusion] Yupingfeng capsule combined with western medicine in the treatment of chronic eczema has satisfactory curative effect and no serious adverse reactions. It is worth popularizing.
作者
曹静
CAO Jing(Fuzimiao Temple Community Health Service Center,Nanjing 210001,China)
出处
《实用中医内科杂志》
2019年第3期45-48,共4页
Journal of Practical Traditional Chinese Internal Medicine
关键词
慢性湿疹
浸淫疮
卫表不固
玉屏风胶囊
氯雷他定
复方氟米松软膏
白介素-10
白介素-2
血清免疫球蛋白E
中药复方
随机平行对照研究
chronic eczema
immersion ulcer
Weibiao Bugu(卫表不固)
Yupingfeng capsule
loratadine
compound flumethasone ointment
interleukin-10
interleukin-2
serum immunoglobulin E
traditional Chinese medicine compound
randomized parallel controlled study
