摘要
本文研究了以2,5-二甲氧基苯胺为原料,经过乙酰化、氯磺化、还原、缩合及酯化反应制得染料中间体2,5-二甲氧基对-β-硫酸酯乙基砜苯胺的合成工艺。经过实验得到最佳工艺条件是:n(2,5-二甲氧基苯胺)∶n(乙酸酐)∶n(氯磺酸)∶n(亚硫酸氢钠)∶n(环氧乙烷)∶n(硫酸)=1.00∶1.14∶10.00∶2.50∶9.00∶1.60,氯磺化反应的保温温度为30℃~32℃。
In this paper, a dye intermediate of 2-[(4-amino-2,5-dimethoxyaniline) suiphonyl] ethyl hydrogen sulphate was obtained by acetylation, chlorosulfonation, reduction, condensation and esterification. And the best process conditions were obtained experimentally: n(2, 5-dimethoxyaniline)∶n(acetic anhydride)∶n(chlorosulfonic acid)∶n(sodium bisulfite)∶n(ethylene oxide)∶n(concentrated sulfuric acid)= 1.00∶1.14∶10.00∶2.50∶9.00∶1.60, the holding temperature of the chlorosulfonation reaction was 30℃~32℃.
作者
于艺伟
YU Yi-wei(Liaoning Fine Chemical Tech. Co., Ltd, Dandong 118301,China)
出处
《皮革与化工》
CAS
2019年第3期21-24,共4页
Leather And Chemicals
关键词
乙酸酐
氯磺酸
环氧乙烷
亚硫酸氢钠
硫酸
acetic anhydride
chlorosulfonic acid
epoxyethane
sodium bisulfite
sulphuric acid
