摘要
目的 探讨血管重建术与腔内栓塞术+对烟雾病继发颅内动脉瘤临床疗效、生活质量及生存时间的影响。方法 研究对象选取南阳市中心医院神经外科2010-01—2014-12收治烟雾病继发颅内动脉瘤患者共110例,根据治疗方法不同分为A组(55例)和B组(55例),其中A组采用血管重建术治疗,B组采用腔内栓塞术+血管重建术治疗,比较2组患者临床疗效、手术前后CSS评分、Barthel指数评分、术后改良Rankin量表评分及随访生存率等。结果 B组患者临床疗效显著优于A组(P<0.05);B组患者治疗后CSS评分和Barthel指数评分均显著优于治疗前、A组(P<0.05);B组患者术后改良Rankin量表评分显著优于A组(P<0.05);2组患者随访1a生存率比较差异无统计学意义(P>0.05);B组患者随访2a生存率显著高于A组(P<0.05)。结论 腔内栓塞术+血管重建术治疗烟雾病继发颅内动脉瘤可有效改善临床症状,促进受损神经功能恢复,提高日常生活质量,并有助于延长生存时间,价值优于血管重建术。
Objective To investigate the influence of two kinds of surgical schemes including indirect cerebral revascularization surgery and intravascular embolization surgery + indirect cerebral revascularization surgery on the clinical efficacy,quality of life and survival rate of patients with moyamoya disease related intracranial aneurysms. Methods 110 patients with moyamoya disease related intracranial aneurysms were chosen in the period from January 2010 to December 2014 and divided according into 2 groups including A group (55 patients) with indirect cerebral revascularization surgery and B group (55 patients) with intravascular embolization surgery + indirect cerebral revascularization surgery;and the clinical efficacy,the CSS score and Barthel index score before and after operation,the modified Rankin scale score after operation and the survival rate with follow up of both groups were compared. Results The clinical efficacy of B group were significant better than A group( P <0.05).The CSS score and Barthel index score after operation of B group were significant better than before operation and A group( P <0.05).The modified Rankin scale score after operation of B group were significant better than A group( P <0.05).There was no significant difference in the survival rate in 1 year with follow up between 2 groups( P >0.05).The survival rate in 2 years with follow up of B group were significant higher than A group( P <0.05). Conclusion Compared with indirect cerebral revascularization surgery,intravascular embolization surgery in the treatment of patients with moyamoya disease related intracranial aneurysms can efficiently improve clinical symptoms,promote the recovery process of damaged nerve function,higher the quality of daily life and be helpful to prolong the survival time.
作者
白新学
周国平
郭春燕
BAI Xinxue;ZHOU Guoping;GUO Chunyan(Department of Neurosurgery,Nanyang Central Hospital,Nanyang 473000,China)
出处
《中国实用神经疾病杂志》
2019年第10期1099-1104,共6页
Chinese Journal of Practical Nervous Diseases
关键词
血管重建术
腔内栓塞术
烟雾病
颅内动脉瘤
Indirect cerebral revascularization surgery
intravascular embolization surgery
moyamoya disease
intracranial aneurysms
