摘要
目的综述不同水碘地区居民碘营养状况和甲状腺相关疾病的研究进展。方法归纳和总结近几年国内外相关文献。结果我国外环境普遍缺碘,居民生活饮用水碘含量大多偏低,通过食盐加碘策略,我国人群碘营养总体达到适宜水平,但在不同水碘地区,特需人群碘营养存在不足或过高的风险;碘缺乏相关疾病得到有效防控的同时,高碘与甲状腺疾病之间的关系引起了人们的关注,高碘可引起甲状腺肿和甲状腺功能减退,但高碘与甲状腺功能亢进、自身免疫性甲状腺炎和甲状腺癌之间的关系还需进一步探讨。结论关注碘摄入来源和人群碘营养,寻找最佳碘摄入范围,为不同人群制定个性化补碘方案,同时应从大样本流行病学调查和基础研究等多方面入手,弄清碘与机体之间关系及相关疾病的致病机制,为疾病的预防和治疗提供依据。
Objective To summarize the study advance of iodine nutritional status and thyroid related diseases of residents in regions with different water iodine. Methods The relevant literatures at home and abroad in recent years were reviewed and summarized. Results Iodine deficiency is common in the external environment of China, and the iodine content in drinking water of residents is generally low. The iodine nutrition level of Chinese people is generally appropriate after implementing salt iodization strategy. However, in the areas with different content of water iodine, the risk of inadequate or excessive iodine nutrition existed in the people with special needs. The iodine deficiency disorders were effectively prevented and controlled. Much attention was paid to the correlation between excessive iodine and thyroid diseases. The goiter and hypothyroidism could be caused by excessive iodine, but the relationships between iodine excess and hyperthyroidism,autoimmune thyroiditis and thyroid cancer needed further studies. Conclusions Attention should be paid to the sources of iodine intake and the iodine nutrition of the population to find out the best range of iodine intake so as to provide reference for the formulation of individualized iodine supplement schemes for different populations. At the same time, the relationship between iodine and the body, and the pathogenesis of iodine and related diseases should be clarified from the aspects of largescale of epidemiological investigation and basic research, so as to provide basis for disease prevention and treatment.
作者
史亮晶
申元英
SHI Liang-jing;SHEN Yuan-ying(Department of Medical Microbiology and Immunology,College of Basic Medicine Sciences,Dali University,Dali,Yunnan 671000,China)
出处
《疾病预防控制通报》
2019年第2期93-95,F0004,共4页
Bulletin of Disease Control & Prevention(China)
关键词
水碘
碘营养
甲状腺疾病
Water iodine
Iodine nutrition
Thyroid disease
