摘要
目的了解医院大肠埃希菌的科室分布、标本分布和耐药特点,为临床治疗相关感染提供依据。方法对1 291株大肠埃希菌的分布和耐药情况进行回顾性分析;使用MicroScan walkAway-96细菌鉴定及药敏分析系统进行细菌鉴定和药敏试验,按照美国临床实验室标准化委员会2015年标准进行判读。结果 1 291株大肠埃希菌主要分离自尿液、呼吸道标本和血液,分别占46.86%、18.98%和14.33%;分离率前三位的科室分别是肾内科、泌尿外科和普外科,分别占分离总数的15.49%、10.92%和10.38%;耐药率均低于10%的药物有亚胺培南、美罗培南、厄他培南、头孢西丁、哌拉西林/他唑巴坦、头孢哌酮/舒巴坦和呋喃妥因。结论大肠埃希菌是泌尿道、呼吸道和血流感染常见的病原菌,临床上应首先选用头孢西丁、哌拉西林/他唑巴坦、头孢哌酮/舒巴坦及碳青霉烯类抗菌药物进行抗感染治疗。对简单尿路感染宜选择呋喃妥因口服治疗。
Objective To understand the section distribution, specimen distribution and drug resistance of Escherichia coli(E.coli) in hospital, so as to provide basis for the clinical treatment of related infection. Methods The distribution and drug resistance of 1 291 strains of Escherichia coli were retrospectively analyzed. Bacterial identification and drug sensitivity test were carried out by Microscan walkway-96 bacterial identification and drug sensitivity analysis, and interpreted according to the American clinical laboratory standardization committee(NCCLS) 2015 standard. Results The 1 291 strains of Escherichia coli are arranged mainly in urine and respiratory tract and blood, accounting for 46.86% and 18.98% and 14.33% respectively;the separation rate of the top three departments were Department of Nephrology, Department of Urology and Department of General Surgery, respectively accounting for 15.49%, 10.92% and 10.38%;the drugs with resistance rate lower than 10% were IPM, MEM and ETP, FOX TZP, SCF and FD. Conclusion Escherichia coli is the common pathogen of urinary tract, respiratory tract and bloodstream infection;clinical should first choose FOX, TZP, SCF and carbapenem antibiotics for anti-infection treatment. Furazolidin should be selected for oral treatment for simple urinary tract infection.
作者
许敏
XU Min(Clinical Laboratory,the People's Hospital of Ningyang County, Ningyang, Shandong 271411 , China)
出处
《中国卫生检验杂志》
CAS
2019年第11期1306-1308,共3页
Chinese Journal of Health Laboratory Technology
关键词
大肠埃希菌
耐药分析
抗菌药物
细菌分布
Escherichia coli
Drug resistance analysis
Antibacterial drugs
Bacterial distribution
